69 
These experiments show that the physiological activity of the two 
samples of Thyraden was approximately the same, in harmony with 
their equal iodine content. Their activity was not far removed from 
that of a thyroid preparation containing approximately the same 
percentage of iodine. Double the amount of Thyraden protected 
against almost twice the dose of acetonitrile. 
Series VIII. 
The physiological activity of two samples of commercial thyroid 
tablets were compared in this series. The tablets were pulverized 
and amounts containing definite quantities of thyroid were fed. 
A. THYROID; 0.38 PER CENT IODINE. 
Date. 
Weight of 
mouse. 
Remarks. 
1908. 
September 24. . . 
18.45 
| Feeding of cakes each containing 0.001 gm. thyroid commenced. 
28... 
17.42 
October 2 
16.95 
Acetonitrile, 23.73 mgms., i._e., 1.4 mgms. per gm. mouse. Survived. 
September 24. .. 
22.00 
Thyroid as above. 
28... 
22. 36 
October 2 
20.82 
3 
September 24. . . 
17.28 
Acetonitrile, 35.39 mgms., i. e., 1.7 mgms. per gm. mouse. Survived. 
Thyroid as above. 
28... 
17.02 
October 2 
15. 10 
3 
September 24. . . 
14.70 
Acetonitrile, 27.18 mgms., i. e., 1.8 mgms. per gm. mouse. Survived. 
Thyroid as above. 
28... 
14.66 i 
October 2 
13.20 
Acetonitrile, 26.40 mgms., i. e., 2 mgms. per gm. mouse. Died 3 hours. 
B. THYROID; 0.38 PER CENT IODINE. 
1908. 
September 24. . . 
13.00 
Feeding of cakes each containing 0.005 gm. thyroid commenced. 
28... 
13.54 
October 2 
11.75 
Acetonitrile, 21.15 mgms., i. e., 1.8 mgms. per gm. mouse. Survived. 
September 24... 
15.18 
Thyroid as above. 
28... 
15.20 
October 2 
11.86 
Acetonitrile, 32.20 mgms., i. e., 2.8 mgms. per gm. mouse. Survived. 
September 24... 
16.40 
Thyroid as above. 
28... 
15.72 
October 2 
13.58 
3 
Acetonitrile, 47.46 mgms., i. e., 3.5 mgms. per gm. mouse. Survived. 
September 24. . . 
15.85 1 
Thyroid as above. 
28... 
16.12 
October 2 
14.49 
3 
Acetonitrile, 60.86 mgms., i. e., 4.2 mgms. per gm. mouse. Survived. 
