73 
In the present work we were chiefly interested in determining if 
there is a relation between the percentage of iodine in different 
thyroid preparations and their effect upon the resistance of rats to 
acetonitrile. The following experiments show that there is such a 
relation and that the degree of activity is in general parallel with 
the iodine content : 
Series I. 
A. THYRADEN; 0.085 PER CENT IODINE. 
Date. 
Weight 
of rat. 
Remarks. 
1908. 
June 27 
32 
Feeding of cakes each containing 0.001 gm. thyraden commenced. 
July 1 
31 
6 
30 
Acetonitrile, 30 mgms., i. e., 1 mgm. per gm. rat. Survived. 
June 27 
65 
Thyraden as above. 
July 1 
68 
6 
62 
Acetonitrile, 86.8 mgms., i. e., 1.4 mgms. per gm. rat. Survived. 
June 27 
48 
Thyraden as above. 
July 1 
44 
6 
45 
7 
Acetonitrile, 76.5 mgms., i. e., 1.7 mgms. per gm. rat. Died 5 hours. 
June 27 
33 
Thyraden as above. 
July 1 
34 
6 
32 
7 | 
Acetonitrile, 57.6 mgms., i. e., 1.8 mgms. per gm. rat. Survived. 
B. SHEEP THYROID; 0.11 PER CENT IODINE. 
1908. 
June 27 
29 
Feeding of cakes each containing 0.001 gm. thyroid commenced. 
July 1 
29 
6 
28 
7 
Acetonitrile, 25.2 mgms., i. e., 0.9 mgm. per gm. rat. Survived. 
June 27 
54 
Thyroid as above. 
July 1 
53 
6 
54 
Acetonitrile, 54 mgms., .. e., 1 mgm. per gm. rat. Survived. 
June 27 
31 
Thyroid as above. 
July 1 
30 
6 
29 
Acetonitrile, 31.9 mgms., i. e., 1.1 mgms. per gm. rat. Died 3£ hours. 
June 27 
63 
Thyroid as above. 
July 1 
61 
6 
54 
Acetonitrile, 70.2 mgms., i. e., 1.3 mgms. per gm. rat. Died about 3 hours. 
C. SHEEP THYROID; 0.21 PER CENT IODINE. 
1908. 
June 27 
43 
Feeding of cakes each containing 0.001 gm. thyroid commenced. 
July 1 
42 
6 : 
42 
Acetonitrile, 1.68 mgms., i. e., 0.04 mgm. per gm. rat. Survived. 
June 27 
29 
Thyroid as above. 
July 1 
29 
6 
28 
7 
Acetonitrile, 15.40 mgms., i. e., 0.55 mgm. per gm. rat. Survived. 
June 27 
40 
Thyroid as above. 
July 1 
41 
6 
39 
Acetonitrile, 27.3 mgms., i. e., 0.7 mgm. per gm. rat. Died 1J-2 hours. 
June 27 
61 
Thyroid as above. 
July 1 
58 
6 
54 
Acetonitrile, 54 mgms., i. e., 1 mgm. per gm. rat. Died 1| hours. 
