80 
all three series lost weight; the controls lost 7.1 per cent. Evidently 
the exclusive diet of crackers is not suitable for rats. The loss of 
weight caused by the thyroid was slight if that which would have 
probably been caused by the crackers alone is deducted, and prob- 
ably had nothing to do with the increased susceptibility of the 
animals to morphine. 
Series II. 
A. THYEADEN; 0.085 PER CENT IODIXE. 
Date. 
Weight 
of rat. 
Remarks. 
1908. 
Julv 14 
•57 
Feeding of cates each containing 0.001 gm. thvraden begun. 
18 
56 
99 
55 
Morphine sulphate, 4.95 mgms., i. e.. 0.09 mgm. per gm. rat. Survived. 
Julr 14 
54 
Thvraden as above. 
18 
51 
99 
49 
Morphine sulphate, 5.88 mgms., i. e., 0.12 mgm. per gm. rat. Survived. 
July 14 
52 
Thvraden as above. 
18 
48 
99 
48 
Morphine sulphate, 7.20 mgms., i. e., 0.15 mgm. per gm. rat. Died in 5 hours. 
Julv 14 
SO 
Thvraden as above. 
IS 
78 
99 
ID 
23 
Morphine sulphate, 12.0 mgms., i. e., 0.16 mgm. per gm. rat. Survived. 
B 
. SHEEP THYROID; 0.12 PER CENT IODIXE. 
1908. 
Julv 14 
60 
Feeding of cakes each containing 0.001 gm. thyroid begun. 
* 18 
55 
99 
54 
Morphine sulphate, 4.32 mgms., i. e., 0.08 mgm. per gm. rat. Survived. 
Julv 14 
66 
Thyroid as above. 
* 18 
65 
99 
66 
Morphine sulphate, 7.26 mgms., i. e., 0.11 mgm. per gm. rat. Survived. 
Julv 14 
54 
Thyroid as above. 
* IS 
51 
99 
53 
23 
Morphine sulphate, 6.89 mgms., i. e., 0.13 mgm. per gm. rat. Survived. 
July 14 
60 
Thyroid as above. 
18 
58 
99 
59 
23 
Morphine sulphate, 8.85 mgms., i. e., 0.15 mgm. per gm. rat. Died in 2 hours. 
c. 
. SHEEP THYROID; 0.19 PER CENT IODIXE. 
1908. 
Julv 14 
45 
Feeding of cakes each containing 0.001 gm. thyroid begun. 
18 
41 
99 
40 
Morphine sulphate, 1.60 mgms., i. e., 0.04 mgm. per gm. rat. Survived. 
July 14 
42 
Thyroid as above. 
' 18 
40 
99 
38 
23 
Morphine sulphate, 1.90 mgms., i. e., 0-05 mgm. per gm. rat. Died 4 hours. 
Julv 14 
44 
Thyroid as above. 
' 18 
43 
99 
43 
Morphine sulphate, 2.58 mgms., i. e., 0.06 mgm. per gm. rat. Died 4 hours. 
