95 
Group. 
Weight 
of thyroid 
fresh. 
Weight 
of thyroid 
dried. 
Per cent 
of water. 
Per cent 
of iodine. 
1 
18.03 
4.84 
73. 15 
0. 129 
2 
25.67 
6. 86 
73. 27 
.111 
3 
14. 09 
3. 99 
71.68 
.106 
4 (fed KI) 
13.25 
3. 35 
74 71 
.148 
5 (fed CHI 3 ) 
25.92 
7. 22 
72. 14 
.30 
The glands of the controls contained from 0.106 to 0.129 per cent 
iodine; those which had received the potassium iodide had 0.148 and 
those which had received the iodoform 0.3 per cent. The glands of 
all five series lost approximately the same per cent of moisture on 
drying; this is additional evidence that they are strictly comparable. 
The following experiments were performed with these preparations : 
i. EXPERIMENTS WITH ACETONITRILE. 
a. Experiments on Mice. 
Series I. 
A. THYROID OF GROUP 2 (NORMAL); 0.111 PER CENT IODINE. 
Date. 
Weight 
of mouse. 
Remarks. 
1907. 
June 5 
12.05 
Feeding of cakes each containing 0.0025 gms. thyroid commenced. 
8 
12. 92 
11 
12.92 
15 
13.07 
16 
12.63 
Acetonitrile, 15.16 mgms., i. e., 1.2 mgms. per gm. mouse. Survived. 
June ~5 
10.73 
Thyroid as above. 
8 1 
11. 07 
11 
10.85 
15... ! 
10.50 
16 
10.75 
Acetonitrile, 15.05 mgms., i. e., 1.4 mgms. per gm. mouse. Survived. 
June 5 
12.95 
Thyroid as above. 
8 
13.42 
11 
11.77 
15 
10.41 
Acetonitrile, 16.66 mgms., i. e., 1.6 mgms. per gm. mouse. Died 3 hours. 
June 5 
14 22 
Thyroid as above. 
8 
13.82 
11 
13.00 
15 
11.60 
Acetonitrile, 23.2 mgms., i. e., 2 mgms. per gm. mouse. Died 1 hour. 
B. THYROID OF GROUP 4 (POTASSIUM IODIDE); 0.148 PER GENT IODINE. 
1907. 
June 5 
11.06 
Feeding of cakes each containing 0.0025 gm. thyroid commenced. 
8 
12.27 
11 
12. 35 
15 
12.00 
Acetonitrile, 19.2 mgms., i. e., 1.6 mgms. per gm. mouse. Survived. 
June 5 
11. 64 
Thyroid as above. 
8 
11.52 
11 
11.52 
15 
12.15 
16 
11.80 
Acetonitrile, 22.42 mgms., i. e., 1.9 mgms. per gm. mouse. Died li hours. 
June 5 
12.74 
Thyroid as above. 
8 
12. 02 
11 
11. 62 
15 
11.11 
16 
10.94 
Acetonitrile, 24.07 mgms., i. e., 2.2 mgms. per gm. mouse. Died 3J hours. 
