105 
E. THYROID OF GROUP 5 (IODOFORM); 0.3 PER CENT IODINE. 
Date. 
Weight 
of rat. 
Remarks. 
1908. 
May 15 
43 
Feeding of cakes, each containing 0.001 gm. thyroid, commenced. 
18 
36 
20 
37 
23 
36 
24 
36 
Acetonitrile, 18 mgms., i. e., 0.5 mgm. per gm. rat. Survived. 
May 15 
38 
Thyroid as above. 
18 
37 
* 
20 
38 
* 
23. 
35 
24 
Acetonitrile, 21 mgms., i. e., 0.6 mgm. per gm. rat. Died 1 to 2 hours. 
May 15 
36 
Thyroid as above. 
18 
34 
20 
35 
23 
33 
Acetonitrile, 23.1 mgms., i. e., 0.7 mgm. per gm. rat. Died 41 hours. 
May 15 
41 
Thyroid as above. 
18 
38 
20 
38 
23 
35 
Acetonitrile, 35 mgms., i. e., 1 mgm. per gm. rat. Died 2J hours. 
F. CONTROLS. 
1908. 
May 15 
41 
18 
38 
20 
37 
23 
38 
May 15 
41 
18 
39 
20 
37 
23 
36 
May 15 
50 
18 
46 
20 
48 
23 
44 
24 
May 15 
69 
18 
64 
20 
65 
23 
62 
24 
May 15 
42 
18 
38 
20 
38 
23 
37 
Feeding of cakes without thyroid commenced. 
Acetonitrile, 87.4 mgms., i. e., 2.3 mgms. per gm. rat. Survived. 
Cakes as above. 
Acetonitrile, 100.8 mgms., i. e., 2.8 mgms. per gm. rat. Survived. 
Cakes as above. 
Acetonitrile, 127.6 mgms. i. e., 2.9 mgms. per gm. rat. Survived. 
Cakes as above. 
Acetonitrile, 186 mgms., i. e., 3 mgms. per gm. rat. Died 21 hours. 
Summary . 
as follows: 
-The results of the above experiments may be tabulated 
Gm. thy- 
roid in 
each cake. 
Percentage 
of iodine 
in thyroid. 
Mm. I in 
thyroid of 
each cake. 
Fatal dose of aceto- 
nitrile in mgms. 
per gm. 
Recovered. 
Died. 
A 
0.0005 
0.111 
0.00055 
1.8 
2.1 
B . . 
.0005 
.300 
.00150 
1.3 
1.5 
C 
.0015 
.111 
.00166 
1.2 
1.3 
D 
.003 
.111 
.00333 
.9 
1.0 
E 
.001 
.300 
.00300 
.5 
. 6 
F. Controls. 
2.9 
3.0 
