Ill 
D. THYROID OF GROUP 5 (IODOFORM); 0.3 PER CENT IODINE. 
Date. 
Weight 
of mouse. 
Remarks. 
1908. 
July 13 
15. 91 
Feeding of cakes, each containing 0.001 gm. thyroid, commenced. 
17 
14. 88 
21 
14.90 
Acetonitrile, 19.37 mgms., i. e., 1.3 mgms. per gm. mouse. Survived. 
July 13 
17. 39 
Thyroid as above. 
17 
16. 33 
21 
16.20 
Acetonitrile, 30.78 mgms., i. e., 1.9 mgms. per gm. mouse. Survived. 
July 13 
14. 52 
Thyroid as above. 
17 
13. 72 
21.; 
12. 63 
22 
July 13 
17. 78 
Acetonitrile, 26.52 mgms., i. e., 2.1 mgms. per gm. mouse. Survived. 
Thyroid as above. 
17 
16. 40 
21 
17. 12 
Acetonitrile, 41.09 mgms., i. e., 2.4 mgms. per gm. mouse. Died 3 hours. 
E. CONTROLS. 
1908. 
July 13 
14. 35 
Feeding of cakes without thyroid commenced. 
17 
13. 98 
21 
13. 53 
Acetonitrile, 3.25 mgms., i. e., 0.24 mgm. per gm. mouse. Survived. 
July 13 
13.25 
Cakes as above. 
17 
12.83 
21 
12. 96 
Acetonitrile, 3.24 mgms., i. e., 0.25 mgm. per gm. mouse. Died 1 hour. 
July 13 
14.20 
Cakes as above. 
17 
13.03 
21 
11.50 
22 
Acetonitrile, 2.99 mgms., i. e., 0.26 mgm. per gm. mouse. Died 2 \ hours. 
SUMMARY. 
Gm. thy- 
roid fed 
daily. 
Percentage 
of iodine 
in thyroid. 
Mgm. I in 
thyroid 
fed daily. 
Fatal dose of aceto- 
nitrile in mgms. 
• pergm. 
Recovered. 
Died. 
A 
0. 001 
0. 12 
0. 0012 
0.45 
0.55 
B 
.001 
. Ill 
.00111 
.65 
C 
.001 
.21 
.0021 
1.6 
1.9 
D 
.001 
.3 
.0030 
2.1 
2.4 
E, Controls 
.24 
.25 
The results are very similar to those obtained with the thyroid of 
Series A. The thyroid, the iodine content of which had been increased 
by the administration of iodoform, was much more active in protect- 
ing mice against acetonitrile than was that of the normal dogs. 
