28 
(d) Solubility factors. 
( e ) Dose and uses. 
(/) Special incompatibilities. 
( g ) Necessary precautions for keeping. 
Ibid., pp. 143-145, etc. 
Barthe, L., and others propose the establishing of official labora- 
tories for the examination of new remedies and determining their 
composition. 
Yidal, L., discusses this proposition at some length and considers 
such a central bureau as being a necessity. He also quotes the litera- 
ture and gives a number of references bearing on this subject. — Bull. 
Sc. pharmacol., Paris, 1905, v. 12, pp. 223-226. 
Barthe, L., discusses the subject further, and his article is followed 
by one from G. Pegurier. — Ibid., pp. 336-337 and 338-339. 
Zernik, F., recounts the new remedies and innovations recorded 
during the year just past. — Ber. d. pharm. Gesellsch., Berl., v. 15, 
1905, p. 6 ff. 
Riedel, in a review covering 52 pages, gives a summary of the new 
remedies introduced during the year 1904. — Riedel’s Mentor, 1905, 
pp. 79-131. 
Astre, Ch., gives a review of the composition and therapeutic prop- 
erties of a number of the newer synthetics and makes an attempt to 
classify them and to determine their action and uses from their 
chemical composition. — Bull, de Pharm. du Sud-Est, 1905, v. 10, pp. 
169-178. 
Schieffelin, Wm. Jay, in an abstract of a paper presented at the 
Lewis and Clark Pharmaceutical Congress outlines the history of 
synthetic remedies and their manufacture. — Am. Druggist, Y. Y., 
1905, v. 47, p. 67, ff. 
5. DOSES. 
Leffman, Henry, feels that one effect of giving the dose of the vari- 
ous remedies will be to encourage the putting up of medicines by 
druggists without a physician’s prescription. He also expresses the 
fear that the prescribing of “ average doses ” may lead to overdos- 
ing. — Med. Yews, Y. Y., 1905, v. 87, p. 1276. 
Wilbert, M. I., quotes the directions of the convention with refer- 
ence to doses, and says : 
In executing these indisputably plain and explicit instructions the members 
of the committee on revision can not be said to have followed them too closely. — 
Am. J. Pharm., Phila., 1905, v. 77, p. 357. 
Williams, S. W., criticises the metric dose and its equivalent in the 
old system as presented in the pharmacopoeia. — Drug. Circ. & Chem. 
Gaz., Y. Y., 1905, v. 49, p. 308. 
