113 
Patein, G., outlines a method for the detection of antipyrine in 
pyramidon which depends upon the fact that antipyrine reacts with 
formaldeh}'de in the presence of hydrochloric acid to form dianti- 
pyrine methane, whereas pyramidon does not. — Abstr. in Pharm. J., 
Lond., 1905, y. 21, p. 361. 
Lemaire, P., (Bull. Soc. Pliarm., Bordeaux) has devised a method 
for ihe determination of antipyrine which depends on the fact that 
antipyrine combines with picric acid, forming an almost insoluble 
crystalline compound. A colorimetric method can also be used in 
the determination. — Abstr. in Analyst, London, 1905, v. 30, p. 22. 
APOCYNUM. 
Frye and Blodgett make a contribution to the life history of 
A. androscemifolium. — Bot. Gaz., Chicago. 1905, v. 10, pp. 19-53. 
Lloyd, John Uri, points out that this American drug has been con- 
fused with its common namesake, the Indian hemp of India. The 
term Indian hemp, he believes, should be dropped and the name 
Canadian hemp employed, if a common name for it is necessary. 
The common name of apocynum (Indian hemp) refers to its use as 
a fiber plant by the aborigines of America, just as a common name of 
Cannabis indica (Indian hemp) connects it with the use of that fiber 
plant throughout the world. — Pharm. Review, 1905, v. 23, p. 298, 
Rusbv, H. H., believes that the indiscriminate use of several species 
of apocynum has discredited the drug and caused it to fall into dis- 
use, When an active article is employed he believes it to be but little 
inferior to strophanthus. — Merck's Rep., X. Y., 1905, v. 11, p. 212. 
Eberle, E. G., mentions apocynum among the medicinal plants of 
Texas. — Proc. Am. Pharm. Ass., 1905, v. 53, p. 301. 
Keys, Jerome, discusses the use of A. cannabinmn in dropsy and 
obesity. — Abstr. in Hahneman. Month., Phila., 1905, v. 10, p. 397. 
APOMORPHIlSTiE HYDROCHLORIDUM. 
Francis, John M., points out that the specifications and the tests 
of the U. S. P., VIII, for apormorphine hydrochloride are complete, 
and that compliance with them should be insisted on. As this sub- 
stance is prone to decomposition it should not be overstocked. — Bull. 
Pharm., Detroit, 1905, v. 19, p. 361. 
Halle, Walter L., in a paper on the present status of our knowledge 
of morphine, discusses the structural formula for apomorphine and 
the relation of that substance to other derivatives of morphine. — 
Chem. Ztg., Cothen, 1905, v. 29, p. 1267. 
Pschorr, Robert (D. R. P. 158620), describes quarternarv salts of 
apomorphine which are more stable and more readily crystalized than 
77439— Bull. 49—09 8 
