135 
isolated mammalian heart finds that caffeine increases the work of 
the heart and strengthens the heart contractions. The number of 
contractions per minute is increased but the nutrition of the heart is 
decreased. — Biochem. Centralbl., v. 4, 1905, p. 495. 
Douglass, Malcolm E., suggests the use of caffeine in cardialgia, 
spasmodic asthma, hemicrania, and nervous palpitations ; it is a direct 
heart stimulant. “ Used in sleeplessness and drowsiness ; lithaemic 
conditions and uraemic coma.” Caffeine Citratis Effervescens is a 
most pleasant method of administration. — Hahneman. Month., Phila., 
1905, v. 40, p. 851. 
CAFFEINA CITRATA. 
“A junior Pharmacist” in “Notes on official galenicals” suggests 
the use of much less than the Ph. Brit. IV quantity of distilled 
water. He suggests dissolving 1 pound of citric acid in 10 fluid 
ounces of water, then adding the caffeine and evaporating. — Pharm. 
J., Bond., 1905, v. 21, p. 462. 
Francis, John M., believes that the new formula for effervescent 
citrated caffeine owing to the omission of the sugar is a decided 
improvement. — Bull. Pharm., Detroit, 1905, v. 19, p. 363. 
CALAMUS. 
Eberle, E. G., mentions calamus among the medicinal plants found 
in Texas. — Proc. Am. Pharm. Ass., 1905, v. 53, p. 304. 
Francis, John M., considers the menstruum for the official fluid 
extract of calamus weak in alcohol. — Bull. Pharm., Detroit, 1905, v. 
19, p. 496. 
CALCII CARBONAS PR^ECIPITATUS. 
Lyons, A. B., points out that — 
No titration test is given, although such tests can be very easily made. 
There is no test given for the common impurity of magnesium, but this omis- 
sion may have been intentional. — Proc. Am. Pharm. Ass., 1905, v. 53, p. 261. 
Patch, Edgar L., reports finding precipitated carbonate of calcium 
containing 2.1 per cent of material insoluble in dilute acids, and 
another sample containing sand, iron, and chloride. — Ibid., p. 183. 
CALCII CHLORIDUM. 
Stokes, H. H., reports the use of calcium chloride in two cases of 
haemorrhage, with apparent good results. — Brit. M. J., London, 1905, 
i, p. 183. 
Godfrey, Jas. M., reports a case of haemophilia treated with cal- 
cium chloride. — Hahneman. Month., Phila., 1905, v. 40, pp. 126-128. 
CALCII HYPOPHOSPHIS. 
Havenhill, L. D., examined a sample of calcium hypophosphite 
which was found to be very impure. — Proc. Kansas Pharm. Ass., 
1905, p. 91. 
