150 
tions. — J. Soc. Chem. Ind., Lond., 1905, v. 24, p. 1228 (from Ber. 
1905, v. 38, pp. 3558-3586). 
CHRYSAROBINUM. 
Oesterle, O. A., presents a comparative study on the melting point 
of chrysophanic acid, as determined by several authors, and the 
causes for the variations that have been noted. — Arch. d. Pharm., 
1905, v. 243, p. 434. 
Oesterle, O. A., presents a study of chrysophanic acid and its re- 
lated compounds. — Schweiz. Wchnschr. f. Chem. u. Pharm., 1905, v. 
43, p. 502. 
CIMICIFUGA. 
Lloyd, John Uri, points out that cimicifuga is likely to be contami- 
nated with other species of cohosh or actsea, not as intentional adul- 
terations, however, as others are rarer than the more common black 
cohosh. — Pharm. Rev., 1905, v. 23, p. 300. 
CINCHONA. 
Francis, John M., expresses the belief that the ether-soluble stand- 
ard for cinchona alkaloids is not an improvement over the assay 
standard hitherto employed for the drug. — Bull. Pharm., Detroit, 
1905, v. 19, p. 528. 
Dohme finds that the ether-soluble alkaloids in cinchona varied 
from 5.8 per cent in 1902 to 7.1 per cent in 1901. He also reports 
finding a variation of total alkaloids in red cinchona from 6.05 per 
cent in 1903 to 6.85 per cent in 1901. — Apothecary, Boston, 1905, v. 17, 
p. 942. 
Vanderkleed, Charles E., reports three assays varying from 3.42 to 
9.0 per cent. He also points out that each lot of cinchona needs a 
careful assay, as the market is full of the drug assaying less than 5 
per cent total alkaloid. — Proc. Penna. Pharm. Ass., 1905, p. 55. 
Howard (from Pharm. J.) has analyzed a false calisaya and found 
5.14 per cent of quinine, 0.24 per cent of cinchonidine, 0.34 per cent 
of cinchonine, 0.16 per cent of chinidine, and 0.56 per cent of amor- 
phous alkaloids. The bark resembled that of C. boliviano. Wed. and 
of C. calisaya var. morada Planch. The original plant is evidently 
closely related to Cinchona calisaya. — Pharm. Zentralh., 1905, v. 46, 
p. 670. 
Naylor, W. A. H., discusses Alcock’s proposition to use an alcoholic 
solution of potash in place of the aqueous one prescribed in the Ph. 
Brit., IV. He points out that, contrary to other observers, the process 
has usually yielded higher results than the authoritative standard. — 
Pharm. J., Lond., 1905, v. 21, p. 124. 
Fromme, G., points out that the gravimetric determination of the 
alkaloids in cinchona is the only reliable means for determining the 
