265 
serum and is the official standard prepared under the act approved 
July 1, 1902. He also presents a comprehensive bibliography of 
the literature bearing on the standardization of diphtheria anti- 
toxin. — -Bull. No. 21 Hyg. Lab., U. S. P. H. & M.-H. S., 1905 (April), 
92 pp. 
The Spanish Pharmacopoeia includes this article under the title 
“ Suero Antidifterico,” the Latin title being “ Serum Antidiphthe- 
ricum.” It is defined as being serum obtained from the blood of 
animals (preferably the horse) of guaranteed health and immunized 
artificially against diphtheria. The liquid serum and the dried are 
defined and the method for its employment is outlined. — Farmacopea 
Oficial Espanola, 1905, pp. 539-540. 
Layson, L. C. (American Medicine, 1905, October 28), reports a 
laboratory stud}^ of antidiphtheritic serum. He concludes that 
serums retain their activity much longer than has heretofore been 
supposed, being unimpaired or but slightly modified at the end of 
two, four, or even five years. — J. Am. M. Ass., 1905, v. 45, p. 1520. 
“The New Idea ” discusses the production of antitoxin sera, the 
tests that are made in connection with the production of antidiph- 
theritic serum, and criticises the immunizing dose prescribed in the 
U. S. P., VIII. — The New Idea, 1905, v. 27, pp. 41-47, 64-65, 136, 
and 145. 
McCollom (Bost. M. & S. J., 1905) records the experience of nine 
years in the treatment of diphtheria with antitoxin. — Therap. Gaz., 
1905, v. 29, p. 620. 
Wainwright, J. W., discusses the general subject of serum 
therapy. (International Clinics, 1905, v. 3.) J. Am. M. Ass., 1905, 
v. 45, p. 1608. 
Street, St. C. (Med. Bee., 1905, November 12), reports a case in 
which 67,000 units of antitoxin were administered before there was 
any response to treatment. Ibid., p. 1758. 
SIN APIS. 
Eberle, E. G., mentions Sinapis alba among the medicinal plants of 
Texas. — Proc. Am. Pharm. Ass., 1905, v. 53, p. 305. 
Kebler, Lyman F., reports powdered mustard adulterated with 
turmeric colored wheat starch. — Ibid., p. 186. 
Tschirch and Oliva present a comprehensive study of the several 
seeds of the crucifera, with particular reference to the variations 
found in the seed coat of the several species of mustard. — Schweiz. 
Wchnschr. f. Chem. u. Pharm., 1905, v. 43, p. 614. 
Spaeth, E., points out the difficulty of detecting powdered rape 
seed meal in powdered mustard. He enumerates among the more 
common adulterants of powdered mustard, wheat flour, corn meal, 
