286 
first portion of the ointment, stir well, until cool. — Drug. Circ. & 
Chem. Gaz., N. Y., 1905, v. 49, p. 220. 
VIRUS VACCINICUM. 
von Prowazek, S., discusses the several views advanced with re- 
gard to the nature of vaccine and reports a study of the character of 
structures found in the virus. He also reports a study of the struc- 
tural changes produced in the skin of the calf infected with vaccine 
virus. — Arb. a. d. K. Gesundheitsamte, 1905, v. 22, pp. 525-541. 
Warfield, Louis M., reports a case of erythema multiforme follow- 
ing vaccination. — J. Am. M. Ass., 1905, v. 45, p. 852. 
An editorial discusses vaccination during the eruptive stage of 
smallpox. — Ibid ., p. 723. 
VALERIANA. 
The annual report of Philip Roder, Wien, records the examination 
of a sample of valerian which yielded 8.86 per cent of water and 10.42 
per cent of ash.— Pharm. Post, Wien, 1905, v. 38, p. 391. 
Kionka, H. (Arch, internal, de Pharmacod. et de Therap, 1905, 
v. 15, p. 279), reports experiments with various kinds of valerian. 
He believes that the content of oil is the important factor and that 
this is dependent on soil conditions. — Biochem. Centralbl., 1905, v. 4, 
p. 452. 
Gadd, H. Wippell and Sydney C., assert that valerian should not 
yield more than 9 per cent of ash; they also propose a solid extract 
standard (3 per cent) for the ammoniated tincture of valerian of the 
Ph. Brit.— Pharm. J., Bond., 1905, v. 21, p. 520. 
VANILLA. 
Hennings, R., discusses the economic conditions prevailing in the 
drug market, relating to vanilla, and enumerates the chief sources 
of supply for Germany. — Der Tropenpflanzer, Berlin, 1905, v. 9, pp. 
87-89. 
An abstract from a paper by J. H. Dow (Bull. Pharm.) describes 
some of the tricks resorted to, in connection with vanilla beans, and 
cautions against the use of manipulated beans. — Canad. Druggist, 
1905, v. 17, p. 178. 
Caeser and Loretz discuss the several varieties of vanilla now on 
the market. They appear to regard the Bourbon bean as being the 
most desirable, with the Comoro, Seychelles, and Madagascar varie- 
ties as being closely allied to the former. — Geschafts-Ber. von Caeser 
& Loretz, in Halle a. S., 1905, p. 37. 
Spaeth, E., points out that the generally accepted definitions for 
vanilla are not satisfactory. Sufficient data are not included for the 
recognition of the cheaper grades of vanilla and vanillons. The 
