288 
Caeser and Loretz announce that they prepare a 1 to 9 mixture of 
vanilla with cane sugar that will serve as a flavoring ingredient in 
place of the widely used essence or tincture of vanilla. — Geschafts- 
Ber. von Caesar & Loretz, in Halle a. S., 1905, p. 19. 
VANXLLINUM. 
An editorial characterizes vanillin — 
As ratlier a strange addition to the pharmacopoeia, as it has no medicinal use 
and does not enter into any official pharmaceutical product. — Drug Topics, 1905, 
v. 20, p. 199. 
Schimmel & Co. assert that adulteration of vanillin is still carried 
on extensively. A sample recently examined proved to consist of at 
least 50 per cent of terpin hydrate. The terpin hydrate isolated tvas 
recognized by its melting point, and by the fact that the odor of ter- 
pineol occurred when it was heated with dilute sulphuric acid. — 
Semi-Ann. Rep., Schimmel & Co., 1905, Apr.-May, p. 120. 
Fitzgerald, Francis A. J., refers to the production of vanillin by 
the oxidation of eugenol by means of ozone, thus obviating the sec- 
ondary products or disturbing influences that are possible by the use 
of other oxidizing agents. — Ztschr. f. angew. Chem., 1905, v. 18, 
p. 1743. 
An abstract from La Revue des produits chimiques discusses the 
method of preparing vanillin and protocatechuic aldehyde from iso- 
safrol. — Paint, Oil, and Drug Rep., 1905, Aug. 28, p. 40. 
Rosen thaler, L., discusses the color reactions that take place with 
substances of the ketone class and with a number of essential oils. 
The latter he classifies in four groups, as they produce green, violet, 
blue, or bluish green colorations. — Ztschr. f. analyt. Chem., 1905, v. 
44, pp. 292-301. 
Kutscheroff, M., discusses the so-called vanillin reaction of the ke- 
tones and points out a number of imperfections and shortcomings. — 
Ibid ., p. 622. 
Hartwich and Winckel (Arch. d. Pharm.) show that a large num- 
ber of phenols (and tanning substances) give definite color reactions 
with a solution of vanillin in hydrochloric acid, in the cold and when 
heated. — Semi- Ann. Rep., Schimmel & Co., 1905, Oct.-Nov., p. 111. 
La Wall, Charles H., discusses the behavior of vanillin toward the 
formaldehyde tests and presents a tabulated record of a number of 
experiments. He points out that under some conditions vanillin is 
liable to be mistaken for formaldehyde.— Proc. Pennsylvania Pharm. 
Ass., 1905, pp. 200-202. 
Kastle, J. H., outlines a simple method for distinguishing between 
coumarin and vanillin. The reagent used is a mixture of 5 cc. of 
phenol and 5 cc. of pure concentrated sulphuric acid. — Bull. No. 26, 
Hyg. Lab., U. S. P. II. and M.-H: S., pp. 33-35. 
