40 
Table No. 18 . — Sensitizing action of euglobulins — Continued. 
G. P. No. 
G. P. 
weight. 
First injection. 
Inter- 
val in Second injection, 
days. 
Result. 
105 
0.001 c. c. euglobulins 
(Natl. IX), subcutane- 
ously. 
229 ■ 6 c. e. normal horse (Frank) 
serum, intraperitoneally. 
Dead in 60 min- 
utes. 
104 
0.01 c. e. euglobulins 
(Natl. IX), subcutane- 
ously. 
229 8 c.c. normal horse (Frank) 
serum, intraperitoneally. 
Marked symp- 
toms. 
103 
0.01 c. c. euglobulins i 
(Natl. IX), subcutane- 
ously. 
229 6 c.c. normal horse (Frank) 
serum, intraperitoneally. 
Dead in 25 min- 
utes. 
102 
0.01 c. c. euglobulins 
(Natl. IX), subcutane- 
! ously. 
229 6 c. c. normal horse ( Frank) 
serum, intraperitoneally. 
. No symptoms. 
101 
0.1 c. c. euglobulins 
(Natl. IX), subcutane- 
ously. 
229 6 c.c. normal horse (Frank) 
serum, intraperitoneally. 
M a r k e d symp- 
toms. 
100 
1 c. c. euglobulins 
(Natl. IX), subeutane- 
[ ously. 
229 6 c.c. normal horse (Frank) 
serum, intraperitoneally. 
Dead in 40 min- 
utes. 
IMMUNITY. 
In order to determine whether there is any difference in the immu- 
nity conferred when the second injection is given in the brain and 
the immunity tested by an intraperitoneal injection, or vice versa, 
we took a number of sensitive guinea pigs and divided them into 
three lots. The first series received the second injection of serum 
into the brain, and the animals were tested twenty-four hours later 
for their immunity by intraperitoneal or subcutaneous injections. 
The second series received their intoxicating injection intraperi- 
toneallv, and the animals were tested for immunity one day later, 
either by injections into the brain or subcutaneously. 
The third series received their intoxicating dose subcutaneously 
and were tested one day later intraperitoneally or intracranially. 
There was apparently no difference in the subsequent immunity, 
whether the injection was given subcutaneously, intraperitoneally, 
or intracranially. 
