34 
Cultures . — After forty-eight hours in the incubator all cultures 
remained sterile, except one from the liver and one from the kidney. 
The serum culture from the liver developed one colon}" of a staphylo- 
coccus, which remained white after seventy-two hours’ growth (pre- 
sumably Btapliylococcus pyogenes aThus). 
On the serum culture from the kidney there developed a few colo- 
nies of a small bacillus which in broth, on serum, plain agar, and in 
and on litmus dextrose agar gave the appearance and the reaction of 
Bacillus coli. c. 
Case 121, 1903. 
Mrs. L. M., age 30, born in Germany, residence near Rock Creek 
clubhouse. (See map, p. 8.) Mother of child H. M., case lOT, 
1902. 
Had not been away from home since October, 1902, and there had 
been no visitors at the house since last fall; husband had not been to 
Missoula since winter. These details are mentioned to show the iso- 
lation of the locality and the impossibility of infection from the Bitter 
Root Valley. 
Two months pregnant. Had been in good health for past year and 
spent considerable time shooting near home and clubhouse during the 
spring. All the members of family had been frequently bitten by 
ticks during spring of 1903. As soon as ticks were discovered they 
were removed by ammonia or whisky, and lately by applying carbolic 
acid. 
On May 3 a tick was removed from patient over left breast and 
another over left scapula; ammonia only was used. 
On May 10 she complained of headache, backache, and nausea; w"ent 
to bed for a few hours. 
May 11, had a distinct chill, followed by considerable fever. 
May 12 and 13, felt better in morning but worse in evening. 
May 11, confined to bed and Dr. Parson called, but he was unable 
to go, and Dr. Brown went on the 15th. He found the patient with 
temperature of 103°, pulse 120, suffering with severe pain in back 
and limbs, tongue with a heavy white coat; nausea. A few small red 
spots were noticed on ankles, legs, and knees; none on face or chest; 
few on anterior aspect of wrists. 
May 16, temperature 103°, pulse 120, spots beginning to appear on 
back and arms. 
May IT, patient brought to Missoula and placed in Dr. Parson’s 
private hospital. Seen at 8 p. m. by Drs. Brown, Wilson, and Ander- 
son. Temperature 102°, pulse 126, full and strong. Headache, 
backache, soreness of muscles of legs and arms. Tongue with white 
coat in center and red tip and edges. Small scattered red spots, most 
plentiful on thighs and back, none on face, few on chest, a very few 
