29 
Soluble in water ( 1 : 18 . 7 ) and alcohol ( 1 : 1 . 3 ), readily in glycerin and 
acetone. It is not affected dilute acids, but is decomposed, on 
warming with alkali hydroxides, 3delding chloroform; it behaves in 
this respect like chloral h^^drate, and is, hence, incompatible with 
alkalies. Chloral is formed b}^ its decomposition in the bod}^; the 
formamide which is formed at the same time is supposed to stimulate 
the circulation and thus counteract the depression caused by the 
chloral. 
Dose. — ‘‘Average dose: 1 Gm. (15 grains).” (U. S. P.) 
Caution. — Keep in amber-colored, well-stoppered bottles. It is 
easily decomposed in solution by heat; hence heat should not be used 
in preparing aqueous solutions. Avoid combination in full dose 
with other drugs of a similar pli3^siologic action, for example, Sul- 
phoneth3dmethane {trional)^ Sulphonmethane {suljyhonal)^ H3^drated 
Chloral, etc. 
Allied Compounds.— Chloral, like other aldeh3"des, forms maiw addi- 
tion products more or less comparable with chloralformamide. Thus, 
with eth3d carbamate, chloral unites to form uralium ; with dextrose 
it forms chloralose; with antip3uine, hyjmal; with am3dene h3"drate, 
dormiol^ etc. 
Croton chloixil (But3d-chloral H3"dras, Br. P.) is trichlorbut3dalde- 
h3^de hydrate (CH3CHClCCl2CH(OH)2). Other tri-chlor substitution 
products recently proposed as hypnotics are Moretone or cuitson 
(trichlorpseudobut3dalcohol or acetone-chloroforni) and isopral (tri- 
chlorisopropyl alcohol). 
CINNALDEHTDUM. 
Ciuiiamic Aldehyde. 
CeH^CH-.CH.COH 
Obtained from oil of cinnamon or prepared S3mtheticall3". It is the 
chief and essential constituent of oil of cinnamon, and should be 
present to the extent of about 75 per cent 133- volume in a good oil. 
Character. — A colorless liquid, having a cinnamon-like odor and a 
burning, aromatic taste. It ma3^ be used for nearl3^ all purposes in 
place of the official oil of cinnamon. Pure S3mthetic Cinnamic Alde- 
h3Ae occurs in the market, and has, to a great extent, displaced the 
natural oil of cinnamon. 
Solubility. — Sparingl3" soluble in water, readih" in alcohol, lixed and 
volatile oils. 
Dose. — “Average dose: 0.05 Cc. (1 minim).” (U. S. P.) 
