40 
Solubility. — Soluble in water (1:53), gl3^cerin (1:1), and easih’ in 
alcohol. Being phenolic in character, it readily dissolves in caustic 
alkalies and forms salts with a large number of acids, one of which 
(the carbonate) has been made official. 
Of late years creosote has been largel}" superseded b}" guaiacol, upon 
which the value of creosote no doubt depends. 
Dose. — “Average dose: 0.5 Cc. (8 minims).” (U. S. P.) 
Caution. — It should be preserved in dark, amber-colored bottles, 
protected from the light. Guaiacol which has become dark from 
exposure to light ma^^ be rendered colorless by redistillation. To be 
used cautiously with other drugs of similar ph^^siologic action, e. g., 
Creosotum, Resorcinol, Phen\dis Salicylas, etc. 
GUAIACOLIS CARBONAS. 
Griiaiacol Carbonate. 
(C6H,(0CH3)0)2.C0 
A guaiacol derivative obtained b}^ the action of carbonyl chloride 
upon sodium guaiacolate. 
Also known as duotal. 
Character. — A white, crystalline, neutral powder, nearly odorless 
and tasteless. 
Solubility. — Insoluble in water; soluble in cold (1:48), more so in 
hot, alcohol; slightl}" solul)le in gl}xerin and fattv^ oils. 
Dose. — “Average dose: 1 Gm. (15 grains).” (U. S. P.) 
Other Guaiacol Compounds. — Numerous combinations of guaiacol with 
other acids, etc., are in the market, such as the benzoate {henzosol), 
benzyl-guaiacol, cacodylate {cacodyl iacol)^ cinnamate {styracol)^ phos- 
phate, salicvlate {guaiacol -salol)^ sulphonate, valerianate {geosot), etc. 
HAMAMELIDIS CORTEX. 
Hamanielis Bark. 
Both the bark and twigs, and the leaves of Ilamamdis mrginiana 
are now^ recognized by the Pharmacopoeia; the former are introduced 
under the above title and the old Hamanielis (U. S. P., 1890) becomes 
Hamamelidis Folia. 
Dose. — “Average dose: 2 Gm. (30 grains).” (U. S. P.) 
HEXAMETH YLEN AMINA. 
Hexametliylenainine. 
(CH,)eN, 
A condensation product of formaldehyde and ammonia. Chemically 
it is hexamethylene tetramine. Also known as aininoform^ ammonio- 
foTinaldehyde^ cystamine^ cystogen^ forming uritone^ and urotropin. 
