52 
tical. both names are used in the U. S. Pharmacopoeia, Eighth Decen- 
nial Revision, as separate headings, because most people are familiar 
with the name Hyoscine but not with Scopolamine. Scopolamine is 
formed by the imion of tropic acid with scopoline. a compound similar 
to tropine. (See Homatropine.) 
In the British Pharmacopoeia Scopolamine Hydrobromide is used as a 
synonym for Hyoscine Hydrobromide: in the German Pharmacopoeia 
only the name Scopolaminum hydrobromicum is retained. 
Dose. — 'Hlverage dose: 0.O005 Gm. = 0..5 milligramme grain).*’ 
(U. S. P.) 
SERUM AMIDIPHTHEEIfUM. 
Aiitidiplitlieric Serum. 
Diphtheria Antitoxin. 
**A fluid separated from the coagulated blood of a horse immunized 
through the inoculation of diphtheric toxin.*' — U. S. Pharmacopoeia. 
The German Pharmacopoeia recognizes also the dried serum. 
Autidiphtheric serum gradually loses its power, the loss in one year 
varying between 10 and .30 per cent. 
“The standard of strength, expressed in units of antitoxic power, 
should be that approved or established , by the U. S. Public Health 
and Harine-Hospital Service.” (U. S. P.) All manufacturers selling 
diphtheria antitoxin in the District of Columbia, or in States other 
than the one in which it is manufactured, must secure a license issued 
by the Secretary of the Treasury on recommendation of the Surgeon- 
General of the Public Health and ^larine-Hospital Service. (F or a full 
discussion of the oflicial standard, see Rosenau. M. J. : The immunity 
unit for standardizing diphtheria antitoxin, Bulletin Xo. 21,* Hygienic 
Laboratory. U. S. Public Health and iUarine-Hospital Service. 1905.) 
Dose. — ‘Leverage dose: 3.000 units. Immunizing dose for well 
persons: 500 units.** (L. S. P.) 
Caution. — Should be kept in sealed glass containers in a dark place 
at temperatures between 1.5^ and 15^ C. (10~ and 59^ F.). 
SODII ARSEXAS EXSICCATES. 
Exsiccated Sodium Arsenate. 
Xa^HAsO^ 
This is the same as the Sodii Arsenas of the British Pharmacopoeia; 
also known as anhydrous sodium arsenate. 
Properties. — An amorphous, odorless, white powder. Permanent in 
dry air. Soluble in 3 parts of water: A'ery soluble in boiling water. 
This is prepared from Sodium Arsenate (already official) by expel- 
ling by heat the seven molecules of water of the latter. The hydrous 
sodium arsenate (Sodii Arsenas. U. S. P.) is efflorescent in dry air 
