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unfit for human consumption. According to a number of authorities 
; hydrogen peroxide is apparently harmless in its effects. Amberg 
(43) quotes the following authorities on this point: Jablin-Gonnet 
(44) fed milk containing hydrogen peroxide to young animals and 
i took it himself for two months without ill effect. Rosam (45) took 
within a period of three months a quantity of hydrogen peroxide, 
' in milk, corresponding to 1,800 cubic centimeters of a 3 per cent 
solution without the least injurious effect, and Vandervelde (46) 
r claims to have shown that hydrogen peroxide favors the action of 
I rennin, j)epsin, trypsin, and galactase. 
Concerning the possibility of injurious effects resulting from the 
: use of fluorides as milk preservatives, it may be said that the evidence 
now at hand goes to show that these substances are irritating poisons 
I of considerable power. That such is the case may be seen from the 
following observations which have been made on their toxicity: 
Rubuteau (47) found that 0.5 gram of sodium fluoride given by 
I the mouth produced sickness in dogs and 0.25 gram by mouth 
produced sickness in rabbits. When injected subcutaneously 0.25 
gram of sodium fluoride proved fatal to rabbits. Kolipinski (48), 
who successfully employed sodium fluoride in minute doses in 
epilepsy, intermittent fever, and sympathetic headache^ observed that 
I 5 grains caused vomiting in a dog, when administered by the mouth, 
and that 3 grains injected into a dog or cat caused death in a 
few hours. The urine in such cases was found to contain small 
amounts of albumen, and to be rich in fluorine, indicating its elimi- 
nation by the kidneys. Schulz (49) found the lethal dose of sodium 
fluoride for rabbits to be 0.2 to 0.4 gram, for dogs 0.3 gram, and for 
frogs 0.005 to 0.006 gram. Heidenhain (50) found the lethal dose 
for dogs to be 0.05 to 0.1 gram per kilo body weight. Weinland (51) 
observed that a 2.1 per cent solution of sodium fluoride killed the 
mucous membrane of the throat of a frog and Gruentzner (52) found 
that at such a concentration living nerves are destroyed. Czrellitzer 
(53) found it to be an active poison for all form of cells, and for 
protoplasm generall}q but states that no satisfactory explanation of 
its toxicity is yet known. Kastle and Loevenhart (54) found it 
highly toxic to lipase, the fat-splitting ferment, and quite recently 
Loevenhart and Pierce (55) have considerably extended these obser- 
vations, and have found that sodium fluoride retards the action of 
lipase when present in a solution of the ferment at the great dilution 
of one to one hundred million. 
Baldwin (56) has called attention to several cases of accidental 
poisoning by sodium fluoride, that came under his observation, in 
which an insecticide consisting of sodium fluoride was mistaken for 
baking powder and used in the making of griddlecakes. In these 
cases violent vomiting and purging followed quickly after the eating 
