33 
Acetanilide-ca ffeine 
[Feeding mice acetanilide 0.050 gram+caffeine citrate 0.020 gram per cake.] 
Date. 
Weight of mice in grams. 
1. 
2. 
3. 
4. 
1909. 
February 11 ■ 
February 13 '. . 
20. 68 
16.68 
14. 00 
13.11 
22. 10 
17. 97 
18. 25 
26.26 
22. 78 
20. 52 
No. 1, dead February 13, '2 days; No. 2, dead February 16, 5 days; No. 3, dead February 16, 5 days; 
No. 4, dead February 16, 5 days. 
A still later series using acetanilide and caffeine mixtures showed 
the following results. The caffeine control mice lived 8, 34, 41, and 
65 days. 
Series III. — Control: Acetanilide. 
[Feeding mice acetanilide 0.050 gram per cake.] 
i 
Date. 
1 
Weight of mice in grams. 
1. ' 
2. 
3. 
18. 25 
16.61 
14.43 
13.32 
4. 
1909. 
March 6 ' 
March 8 
March 11 
March 13 , 
15.20 
13. 99 
11.96 
15. 28 
15. 12 
13.69 
15.08 
13. 23 
12.61 
11.94 
No. 1, dead March 12, 6 days; No. 2, dead March 12, 6 days; No. 3, dead March 14, 8 days; No. 4, dead 
March 14, 8 days. 
Acetanilide-ca ffeine . 
[Feeding mice acetanilide 0.050 gram -f caffeine citrate 0.020 gram per cake.] 
Date. 
Weight of mice in grams. 
1. 
2. 
3. 
4. 
1909 
March 6 ‘ 
March 8 
March 11 
15. 95 
14.65 
13.44 
11.84 
15. 21 
14. 00 
15.88 
13.45 
12.19 
1 
i 
No. 1, dead March 9, 3 days; No. 2, dead March 10, 4 days; No. 3, dead March 11, 5 days; No. 4, dead 
March 13, 7 days. 
Another lot fed smaller amounts of caffeine gave results as follows: 
[Feeding mice acetanilide 0.050 gram+caffeine citrate 0.010 gram per cake.] 
Date. 
Weight of mice in grams. 
1. 
2. 
3. 
4. 
1909. 
March 6 
15.43 
14.78 
16.39 
14. 21 
13. 63 
14. 99 
13. 39 
12. 42 
16.02 
14.82 
14.10 
13.85 
March 8 
March 11 
March 13 . 
No. 1, dead March 10, 4 days; No. 2, dead March 11, 5 days; No. 3, dead March 12, 6 days; No. 4, dead 
March 15, 9 days. 
A summary of the results given in the above tables is given here 
for the sake of comparison. 
176— Bull. 53—09 3 
