Table XI. — To:cidty of pure natural l-adrenalin — Continued. 
Xumber of 
mouse. 
Mg. base 
per gm. 
Body 
weight. 
Total. 1 
Injected. 
Time. 
Died. 
Grams. 
Mg. 
C.c. : 
219 
0. 010 
12 73 
0. 130 
0. 13 1 
Jan. 9, 3.09 p. m 
ooo 
0. 010 
13.58 
0. 140 
0.14 ' 
Jan. 9, 3.15 p. m ' 
225 
0.010 
15.44 
0. 150 
0.15 
Jan. 9, 4.57 p. m | 
Jan. 10, 3.30 a. m. (W.) 
228 
0.010 
13.72 
0. 140 
0. 14 
Jan. 9, 5.05 p. m 
Jan. 10, 5.14 p. m. 
231 
0.010 
15. 77 
0. 160 
0.16 
Jan. 9, 5.12 p. m 
Jan. 9, 5.28 p. m. 
115 
0.012 
13. 74 
0. 165 
0.16 
[ Dec. 9, 5.27 p. m ; 
Dec. 9, 6.30 p. m. (W.) 
217 
0.012 
14.80 
0. ISO 
0. 18 
Jan. 9, 3.05 p. m 
220 
0. 012 
19.83 
0.240 
0.24 : 
1 
Jan. 9, 3.12 p. m 1 
! Jan. 12, 8 a. m. (W.) 
223 
0.012 
17.80 
0.210 
0.21 
Jan. 9, 3.19 p. m 
! Jan. 9, 3.35 p. m. 
226 
0. 012 
1.3. 04 
0. 140 
0.14 
Jan. 9, 4.59 p. m 
Jan. 9, 5.11 p. m. 
229 
0.012 
12.11 
0. 140 
0.14 
Jan. 9, 5.07 p. m 
Jan. 9, 5.26 p. m. 
232 
0.012 
13.22 
0.140 
0. 14 
Jan. 9, 5.15 p. m 
Jan. 9, 522 p. m. 
24 
0. 013 
15. 77 
0.210 ' 
0.21 
Xov. 30, 4.40 p. m 
Dec. 1, 9 p. m. (F.) 
35 
0. 013 
13. 43 
0.180 
0.18 
Dec. 2, 9 “^1 a. m 
Dec. 2, 11 a. m. 
116 
0. 014 
16.78 
0.230 
0.23 
Dec. 9, 5.29 p. m 
Dec. 10, 12,15 a. m. 
12 
0. 0147 
18.27 
0.270 
0.27 
Xov. 28 
1 Xov. 28, 4.40 p. m. (W.) 
0. 017 
18.20 
0. 318 
0.32 
Xov. 23, 1.18 p. m 
8 
0. 017 
17.09 
0.298 
0.30 
Nov. 23 
' Nov. 25, 10 p. m. 
13 
0. 017 
20. 18 
0.350 
0.35 
Xov. 28, 3.18 p. m 
; Xov. 28, 3.29 p. m. 
25 
0. 017 
17.04 
0.300 1 
0.30 
Xov. 30, 4.43 p. m 
Nov. 30, 4.55 p. m. 
26 
0.0218 
16. 75 
0.370 
0.37 
Xov. 30, 4.47 p. m 
Dec. 1, 1.45 a. m. (W.) 
14 
0. 0218 
21.52 
0. 470 
0. 47 
Xov. 28, 3.22 p. m 
Nov. 28, 6.30 p. m. (W.) 
36 
0.022 
17. 97 
0.410 
0. 41 
Dec. 2, 9.23 a. m 
Dec. 2, 9.28 a. m. 
9 
0.026 
12.38 
0.320 
0.32 
Xov. 23, 10.54 a. m 
Nov. 27, 1.50 a. m. (F.) 
10 
0.035 
14.40 
0.500 
0.50 
Nov. 25, 11.23 p. m 
Nov. 26, 6 p. m. (F.) 
15 
0.035 
19.26 
0.590 
1 
0.59 
t 
Xov. 28, p. m 
Nov. 30, 8.55 p. m. (F.) 
F. Found dead at time noted. 
W. Time noted by watchman. 
In order to avoid errors from deterioration the solutions were usually made up just 
before using, 5 mgs. of the base having been weighed up and dissolved in 5 c. c. of Ringer 
solution. The solvent was acidified with hydrochloric acid slightly in excess of 
the amount necessary to transform the adrenalin into the chloride. If more specific 
information is desired as to the age of a solution at the time of any given injection it 
is easily obtained by the aid of the following data in conjunction with the time of 
the injection given in the tables: 
Mice Xos. 12, 13, 14, 15, 16, solution made up about 9 a. m. November 27, 1908. 
Mice Xos. 42 to 46, inclusive, solution made up about 11 a. m. December 2, 1908. 
Mice Xos. 52 to 56, inclusive, solution made up about 9 a. m. December 4, 1908, and 
diluted to 1:5,000. 
Mice Xos. 62 to 66, inclusive, the solution was made up between 9 and 11 a. m. 
December 4, 1908. 
Mice Xos. 72 to 76, inclush'e, the solution was made up 11.50 a. m. December 5, 1908. 
Mice Xos. 72, 73, 74, 75, and 76 had been injected with 0.008, 0.014, 0.017, 0.044, 
and 0.085 mg. of adrenalin, respectively. 
Mice Xos. 82, 83, 84, 85, and 86, solution made up 11.50 a. m. December 5. These 
mice had been injected on December 4 with 0.021, 0.042, 0.069, 0.081, and 0.082 mg. 
of adrenalin, respectively. 
Xos. 112 to 116, inclusive, solution made up 11.30 a. m. December 9. 
Xos. 152 to 160, inclusive, solution made up about 2.30 p. m. January 4, 1909. 
Xos. 215 to 232, inclusive, solution made up between 2 and 3 p. m. January 9. 
