47 
Table XIV. — Toxicity of homorenon hydrochloride — Continued. 
Number of 
M?. base 
Body 
Injected. 
Died. 
mouse. 
pergm. 
weight. 
Total. 
Time. 
141 
0. 994 
Grams. 
19.43 
Mg. 
19. 31 
C. c. 
0. 96 
Dec. 10, 3.6 p. m 
Dec. 10, 3.30 p. m. 
171 
0. 994 
14.50 
14. 41 
0.28 
Jan. 5, 3.2 p. m 
Jan. 5, 3.20 p. m. 
174 
0.994 
13. 20 
13. 12 
0. 26 
Jan, 5, 3.9 p. m 
Jan. 5, 3.31 p. m. 
177 
0.944 
13. 76 
13. 68 
0. 28 
Jan. 5, 3.15 p. m 
Jan. 5, 3.38 p. m. 
243 
0.994 
20. 64 
20. 52 
0. 41 
Jan. 16, 1.21 p. m 
Jan. 16, 1.28 p. m. 
246 
0. 994 
22.59 
22.33 
0.44 
Jan. 16, 1.27 p. m 
Jan. 16, 1.39 p. m. 
249 
0.994 
18.31 
18.12 
0. 36 
Jan. 16, 1.36 p. m 
Jan. 16, 1..55 p. m. 
41 
1.038 1 
19. 47 
20. 21 
0. 92 
Dec. 2, 9 a. m 
Dec. 2, 9.53 a. m. 
172 
1. 137 j 
20. 93 
I 23.80 
0. 48 
Jan. 5, 3.4 p. m 
Jan. 5, 3.15 p. m. 
175 
1. 137 i 
17. 00 
19.53 
0. 38 
Jan. 5, 3.10 p. m 
Jan. 5, 3.29 p. m. 
178 
1. 137 1 
13. 42 
14.78 
0. 30 
Jan. 5, 3.20 p. m 
Jan. 5, 3.47 p. m. 
244 
1. 137 : 
15.22 ! 
17. 20 
0.34 
Jan. 16, 1.22 p. m 
Jan. 16, 2 p. m. 
247 
1. 137 : 
17. 78 
20. 11 
0. 40 
Jan. 16, 1.29 p. m 
Jan. 16, 1.39 p. m. 
250 
1. 137 
22. 37 
1 
25.31 
0.50 
Jan. 16, 1.37 p. m 
Jan. 16, 1.50 p. m. 
PROTOCOLS TO EXPERIMENTS OF TABLE XIV. 
The solutions of homorenon hydrochloride used in the different toxicity experiments 
were made up as follows: 
Nos. 37 to 41, inclusive, 66 mg. homorenon hydrochloride crystals dissolved in 3 c. c. 
of Ringer solution about 8.30 a. m. December 2. 
Nos. 47 to 51, inclusive, 20 mg. of crystals dissolved in 2 c. c. of Ringer solution about 
9 a. m. December 3. 
Nos. 57 to 61, inclusive, 25 mg. crystals dissolved in 2.5 c. c. of Ringer solution 11 a. m. 
December 7. 
Nos. 87, 88, 89, 90, and 91 injected December 4 with 0.89, 1.90, 3.25, 6.18, and 5.23 
mg., respectively, of homorenon, and 92, 93, 94, 95, and 96 were each, respectively, 
injected on December 2 with 0.038 mg. of adrenalin, 0.125, 0.225, 0.518, and 1.45 mg. 
homorenon. 
Nos. 97 to 101, inclusive, 20 mg. crystals dissolved in 1 c. c. of Ringer solution. 
Nos. 122 to 141, inclusive, 20 mg. per 1 c. c. of Ringer solution made up 2 p. m. 
December 10. 
Nos. 122, 123, 124, 125, and 126 had been injected with 0.021, 0.042, 0.069, 0.081, 
and 0.082 mg., respectively, of adrenalin base December 4, and again on December 7 
with 0.040, 0.080, 0.103, 0.128, and 0.130 mg., respectively, of the same drug. 
Nos. 127, 128, 129, 130, and 131 were injected December 4 with 0.890, 1.90, 3.25, 
6.18, and 5.23 mg;, respectively, of homorenon, and again on December 7 with 1.33, 
2.25, 3.25, 6.35, and 6.55 mg., respectively, of the same drug. 
No. 132 was injected December 2 with 0.038 mg. of adrenalin base and on December 
7 with 2.48 mg. homorenon. No. 133 on December 4 and 7, respectively, with 0.890 and 
2.48 mg. of homorenon, while Nos. 134, 135, and 136 were each injected on December 2 
with 0.125, 0.225, and 0.518 mg., respectively, of homorenon, and again on December 
7 with 5.77, 8.23, and 8.07 mg., respectively, of the same drug. 
Finally mice Nos. 139, 140, and 141, respectively, had been injected on December 3 
with 0.554, 0.876, and 2.688 mg., and again on the 7th of December with 2.08, 4.24, and 
9.14 mg. of homorenon. 
Nos. 170 to 178, inclusive, 250 mg. of homorenon hydrochloride crystals dissolved in 
5 c. c. of Ringer, about 2.45 p. m. January 5, 1909. 
