60 
Table XX. — Comparison of time required to cause maximum mydriasis. 
1 
I 
Synthetic dl-. 
Natural 1-. 
Synthetic dl-. 
Concentration of solution. 
Long 
axis. 
Short 
axis. 
Long 1 
axis, j 
Short 
axis. 
Long 1 
axis, j 
Short 
I axis. 
Min. 
Min. 
1 
Min. \ 
Min. 
Min. 
Min. 
1:2,000 
21 
21 
20 
13 
15 
15 
1:5,000 
23 
16 
14 
31 
17 
26 
1:25,000 
56 
38 
31 
24 
61 
54 
1:125,000 
153 
203 
55 
114 
332 
359 
1:625,000 
74 
74 
307 
325 
367 
367 
1:3,125,000 
67 
79 
17 
145 
243 
275 
It will be noticed that one of the axes of the eyes in natural 1-ad- 
renalin nearly always reaches a maximum length before those in 
synthetic dl-adrenalin solution of like concentration. Furthermore, 
solutions less dilute than 1:125,000 are uncertain in their action, the 
dilation time often becoming less than that normal for solutions of 
greater concentration. This is brought out more clearly in Tables 
XVm and XXII, in which it will be seen that the dilation time is 
very irregular for dilute solutions. 
Table XXI. — Mydriatic action of synthetic dl-adrenalin. 
EXCISED FROG’S EYE. 
Experiment 50b. 
1:2,000. 
Experiment 52a. 
1: 5,000. 
Experiment 55a. 
1:25,000. 
1 
Time. 
Long Short 
axis. axis. 
Time. 
Long Short 
axis. axis. 
1 
Time. 
Long Short 
axis. axis. 
P. 7n. j 
1.44 1 
2.50 
M. m; 3L m. 
a 1. 720 o 1. 310 
a 1. 690 a 1. 275 
' P. m. 
1. 46 
M. m. M. m. 
a 1. 810 a 1. 435 
P. m. 
2. 12 
M. m. M. m. 
a 1. 885 “ 1. 815 
i 
3. 1 ' 
i 
a 1.690 a 1.360 
1. 55 
i 
a 1. 876 a 1. 585 
2. 21 
a 1. 980 a 1. 920 
3. 3 ' 
In adrenalin. 
1. 57 
In adrenalin. 
2.23 
In adrenalin. 
3.6 
3 
3.9 
6 
3. 12 
9 
61.745 61.440 
cO. 055 cO. 080 
1 6 1. 885 6 1. 750 
cO. 195 CO. 390 
6 2.095 6 2.010 
c 0. 405 c 0. 655 
1.59 
2 
2.2 
1 
1 ^ 
2.4 
6 1. 900 6 1. 880 
CO. 030 c 0.295 
6 2. 140 6 2. 235 
CO. 270 c 0.650 
6 2. 485 6 2. 460 
c 0. 615 c 0. 875 
2. 26 
3 
2. 28 
5 
2. 30 
6 2. 190 62. 125 
1 c 0.210 c 0.205 
6 2. 205 6 2. 095 
c 0.215 c 0.175 
j 6 2. 225 6 2. 135 
! c 0.245 c 0.215 
1 
a Actual length of axis. Measured in 2 c. c. of Ringer solution at 23 °C. 
& Actual length of axis at time measured. 
cChangein length of axis after the eye is exposed to 2 c. c. of adrenalin solution for the number of 
minutes indicated to left in time column. 
