25 
One hundred and four milligrams agetonitrile contains 65.94 milli- 
grams cyanogen; hence 56.3 per cent of the c^^anogen of the nitrile 
was excreted as sulphocyanate. 
The controls (of the same litter as the above) gave the following 
results : 
Date. 
Weight of 
guinea pig. 
Remarks. 
November 22, 1905 
December 4, 1905 
December 9, 1905 
December 14, 1905.... 
December 21, 1905 
December 29, 1905 
January 5, 1906 
January 12, 1906 
Grams. 
330 
375 
400 
405 
445 
435 
445 
475 
Food as in foregoing, except for the alcohol. 
January 19, 1906 
490 
January 26, 1906 
515 
Febimary 2, 1906 
520 
February 6, 1906 
500 
100 milligrams acetonitrile (0.2 milligram per 
gram). Survived. 
The excretion of cyanogen was as follows : 
Day. 
Cyanogen. 
First day 
Milligrams. 
4.03 
Second day 
.65 
Third day 
1. 56 
Fourth day .• 
8.97 
Fifth day 
3. 51 
Sixth day 
3.64 
Total 
22.36 
One hundred milligrams acetonitrile (the amount injected) con- 
tains 63.4 milligrams cyanogen; hence about 35.2 per cent of the 
cyanogen of the nitrile appeared in the urine as sulphocyanate. 
Comparing this result with that of the above alcohol experiment, 
it wiirbe seen that the guinea pig on alcohol excreted about 1.65 
times as much cyanogen as sulphocyanate as did the normal. 
