26 
The other control experiment gave the following results : 
Date. 
Weight of 
guinea pig. 
Grams. 
November 22, 1905 
December 4, 1905.. 
December 9, 1905.. 
December 14, 1905 
December 21, 1905 
December 29, 1905 
January 5, 1906 
January 12, 1906... 
January 19, 1906... 
January 26, 1906... 
February 2, 1906. . 
February 6, 1906. . 
295 
325 
355 
380 
425 
400 
390 
340 
345 
375 
400 
355 
Remarks. 
Had two young about this time. 
71 milligrams acetonitrile (0.2 milligram per 
gram). Survived. 
The cyanogen excreted was as follows: 
Day. 
Cyanogen. 
First day 
Milligrams. 
3.38 
2.99 
3.51 
1.17 
1. 56 
2.34 
Second day 
Third day 
Fourth day 
Fifth day -. 
Sixth day 
Total 
14.95 
Seventy-one milligrams acetonitrile contained 45 milligrams cyano- 
gen; hence 33.2 per cent of the cyanogen of the nitrile had appeared in 
the urine as sulphocyanate. Thus the guinea pig on alcohol had 
excreted 1.75 times as much cyanogen as sulphocyanate as did the 
normal after corresponding doses of the nitrile. 
Another guinea pig of this series, which had received alcohol for 
several months (during which time its weight had increased from 345 
to 520 grams), died from 95 milligrams acetonitrile (0.2 milligram 
per gram) . And it may be remarked that a few other experiments 
were lost by the death of guinea pig receiving alcohol, for alcohol 
increased the susceptibility of guinea pigs to acetonitrile in the same 
way it did that of mice. 
In the following experiments the excretion of cyanogen was less 
than in the foregoing, but a similar difference between the normal 
and alcohol animals was observed: 
