40 
Solubility. — Soluble in water (1:53), glycerin (1:1), and easily in 
alcohol. Being- phenolic in character, it readily dissolves in caustic 
alkalies and forms salts with a large number of acids, one of which 
(the carbonate) has been made official. 
Of late years creosote has been largely superseded by guaiacol, upon 
which the value of creosote no doubt depends. 
Dose. — “Average dose: 0.5 Cc. (8 minims). ” (U. S. P.) 
Caution. — It should be preserved in dark, amber-colored bottles, 
protected from the light. Guaiacol which has become dark from 
exposure to light may be rendered colorless by redistillation. To be 
used cautiously with other drugs of similar physiologic action, e. g., 
Creosotum, Resorcinol, Phenylis Salicylas, etc. 
GUA1ACOLIS CARDONAS. 
Guaiacol Carbonate. 
(C 6 H 4 (0CH 3 )0) 2 .C0 
A guaiacol derivative obtained b} T the action of carbonyl chloride 
upon sodium -guaiacolate. 
Also known as duotal. 
Character. — A white, crystalline, neutral powder, nearly odorless 
and tasteless. 
Solubility. — Insoluble in water; soluble in cold (1:48), more so in 
hot, alcohol; sligbtty soluble in glycerin and fatty oils. 
Dose. — “Average dose: 1 Gm. (15 grains).” (U. S. P.) 
Other Guaiacol Compounds. — Numerous combinations of guaiacol with 
other acids, etc., are in the market, such as the benzoate ( bemosol ), 
benzyl-guaiacol, cacodylate ( cacodyliacol ), cinnamate ( styrcicol ), phos- 
phate, salicylate {guaiacol-salol ) , sulphonate, valerianate ( geosot ), etc. 
HAMAMELIMS CORTEX. 
Hamamelis Bark. 
Both the bark and twigs, and the leaves of Hamamelis virginiana 
are now recognized by the Pharmacopoeia; the former are introduced 
under the above title and the old Hamamelis (U. S. P., 1890) becomes 
Hamamelidis Folia. 
Dose. — “Average dose: 2 Gm. (30 grains).” (U. S. P.) 
HEXAMETHYLENAMINA. 
Hexamethylenamine. 
(CH 2 ) 6 N 4 
A condensation product of formaldehyde and ammonia. Chemically 
it is hexamethylene tetramine. Also known as aminoform , ammonio- 
formaldehyde , cystamine , cystogen, formin, uritone , and urotropin. 
