Part IL 
THE TOXIC PRINCIPLE. 
\\e added a number of different ferments, alkaloids, and simpler 
chemical substances to horse serum in order to modify, destroy, or 
neutralize its toxic action. All these attempts have so far been found 
unavailing, as will be seen by the following experiments: 
FERMENTS. 
The ferments were added to the horse serum and allowed to stand 
at 15^ C. over night. 
Taka diastase. 
(t. P. No. 5417. Six c. c. antitoxic horse serum (Natl. IX., 19)-]- Taka diastase 
(PDCo. ), subcutaneousl}". Dead, 90 minutes. 
[Previous treatment: 27 days prior, 0.139 c. c. toxine Xo. c. c. antitoxic 
horse serum (A. A 208).] 
Pancreatin. 
G. P. Xo. 5413. Six c. c. same serum pancreatin (PDCo.), subcutaneously. Dead, 
40 minutes. 
[Previous treatment: 27 days prior, 0.139 c. c. toxine Xo. 9-|-6^ c. c. antitoxic 
horse serum (x4. A 208).] 
Rennin. 
G. P. Xo. 5405. Six c. c. same serum -j-rennin (Hansen's junket tablet), subcuta- 
neously. Dead, 50 minutes. 
[Previous treatment: 27 days prior, 0.139 c. c. toxine Xo. 5-j— 5^0 c- c. antitoxic 
horse serum (A, A 208).] 
My rosin. 
G. P. Xo. 5416. Six c. c. same serum -|-my rosin (from white mustard seed), subcu- 
taneously. Dead, 25 minutes. 
[Previous treatment: 27 days prior, 0.139 c. c. toxine Xo. 5-hy^o c- c. antitoxic 
horse serum (A. A 208).] 
Invertin. 
G. P. Xo. 5375. Six c. c. same serum -f invertin (yeast), subcutaneously. Dead, 
80 minutes. 
[Previous treatment: 27 days prior, 0.139 c. c. toxine Xo. 5-bxAo c. c. antitoxic 
horse serum (XYBH 305)]. 
Emulsin. 
G. P. Xo. 5373. Six c. c. same serum -|-emulsin (from almonds), subcutaneously. 
Severe symptoms. 
[Previous treatment: 27 days prior, 0.139 c. c. toxine Xo. 5-f c. c. antitoxic 
horse serum (XYBH 305).] 
Pepsin in acid solution. 
G. P. Xo. 5409. Six c. c. same serum -f pepsin (Wyeth’s) rendered acid with HCl, 
subcutaneously. Severe symptoms. 
[Previous treatment: 27 days prior, 0.139 c. c. toxine Xo. 5-b^^^ c. c. antitoxic 
horse serum (A. A 208).] 
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