19 
children showing eruption following the injection of serum is greatlj^ 
reduced. We thought perhaps this salt might have some influence 
upon the phenomenon produced in guinea pigs by two injections of 
horse serum. Three series of experiments were made with this object 
in view. 
The effect of 0.1 gram of CaCl^ hy mouth for three consecutive days before the second 
injection of horse serum. 
No. 
G. P. 
First injection. 
Interval. 
Second injection. 
Result. 
6065 
6063 
0.14 c.c. toxine 5+6-8 0 
c. c. antitoxic horse 
serum (NYHD. 310), 
subcutaneously; 
then for 3 days be- 
fore second injection, 
0.1 gm. CaCb by 
mouth. 
do 
Days. 
65 
65 
3 c. c. normal horse 
(roan) serum, in- 
traperitoneally. 
do 
IMarked symptoms. 
Dead, 40 minutes. 
6064 
do 
65 
6 c. c. normal horse 
Dead, 3 minutes. 
Mild symikoms. 
! Dead, 20 minutes. 
6057 
do 
65 
(roan) serum, in- 
traperitoneally. 
3 c. c. normal horse 
6062 
0.14 c.c. toxine 5+y|o 
c. c. antitoxic horse 
serum (NYHD. 310), 
subcutaneously; 
then for 3 days be- 
fore second injection, 
0.1 gm. CaCb by 
mouth. 
65 
(roan) serum, in- 
traperitoneallv. 
do 
Effect of 0.1 gram CaCl^ daily for twenty days before the sensitizing inoculation was given^ 
and every other day until the second injection of horse serum, fourteen days later. 
No. 
G. P. 
> 
, First injection. 
Interval. 
Second injection. 
Result. 
0.1 gm. CaCb by mouth 
daily for 20 days; 
then 0. 14 c. c. toxine 
5 + 2 I 0 c. c. antitoxic 
horse serum (S. 1500) , 
subcutaneously; 
then CaCb every 
other day till second 
injection. 
do 
Days. 
14 
3 c. c. normal horse 
Dead, 30 minutes. 
k 
i' 
14 
(roan) serum, in- 
traperitoneally. 
do 
Severe symptoms. 
Marked symptoms. 
Severe symptoms. 
Severe symptoms. 
do 
14 
do 
do. -- 
14 
do 
do 
14 
do 
