26 
EFFECT OF IODINE UPON SPECIFICITY. 
In the following series we not only tested guinea pigs treated with 
horse serum to find out whether they react after an interval to chicken 
serum, and vice versa, but also to ascertain whether the presence of 
iodine in the sensitizing dose modifies the specific nature of the reac- 
tion. The results plainly show that under the conditions of the 
experiment the iodine had no modih'mg action upon the power of 
these serums to sensitize against a second injection of homologous 
serum and also had no power to impair the specific nature of the 
phenomenon. 
Table Xo. 20. — Effect of iodine on specificity. 
G. P. 
No. 
First injection. 
Inter- 
val in 
days. 
Second injection. 
Result. 
1613 
1 c. c. 0.01 per cent chicken serum 
-i-iodine subcutaneously. 
19 
0J2 c. c. chicken serum into 
brain. 
Severe symptoms. 
1604 
do 
19 
do 
Severe symptoms. 
1615 
2 c. c. 0.01 per cent chicken serum 
Aiodine subcutaneously. 
19 
0.2 c. c. normal horse (Teddy) 
serum into brain. 
No symptoms. 
1616 
...do 
19 
do 
No sjTnptoms. 
1617 
1 c. c. 0.01 per cent chicken serum 
+iodine subcutaneously. 
19 
do 
No symptoms. 
1618 
2 c. c. 0.01 per cent normal horse 
(Frank) serum -i-iodine subcu- 
taneously. 
19 
do 
Severe symptoms. 
1619 
1 c. c. 0.01 per cent normal horse 
(F rank) serum -i-iodine subcu- 
taneously. 
19 
; do 
Dead in 4 minutes 
1620 
do 
19 
02 c. c. chicken serum into 
brain. 
No symptoms. 
1621 
2 c. c. 0.01 per cent normal horse 
(Frank) serum -i-iodine subcu- 
taneously. 
19 
do 
No symptoms. 
1622 
1 c. c. 0.01 per cent normal horse 
(Frank) serum -i-iodine subcu- 
taneously. 
19 
do 
No symptoms. 
RELATION BETWEEN MILKS OF VARIOUS SPECIES. 
HUMAN VERSUS COW MILK. 
Eight guinea pigs were sensitized by the subcutaneous injection of 
1 c. c. of human milk. After an appropriate interval they were tested 
with cow’s milk without response. 
A short time later they were again tested with human milk. This 
time most* of them showed severe symptoms. 
Tliis series again indicates not only the specific nature of the 
anaphylactic reaction, hut suggests differences between the protein 
matter in human and in cow’s milk. 
