39 
Massey, Franklin P., says: 
Tbe homoeopath often accuses his old-school brother of overdosing his case, 
when often the average dosage is very nearly the same under both systems 
(especially when using such drugs as potassium, iodide, digitalis, passiflora, 
etc.). Many of these mistaken views could be corrected if all physicians would 
endeavor to honestly inquire into the merits of substances in dispute and make 
a fair comparative study of them. (Of course, we know that much overdosing 
occurs in the old school, but when making such charges we should be specific 
and well able to prove our statement.) — Hahneman. Month., Phila., 1906, v. 41, 
p. 585. 
When the allopath does carefully prove (test) his drugs he comes 
to practically the same conclusions as his brother of the new school. — 
Ibid., p. 591. 
Hawthorne, C. O. (Brit. Med. J., February 10, 1906), states that 
unless official doses are strictly limited and defined they must be con- 
sidered as being a possible danger to free and responsible personal 
prescribing.— J. Am. M. Ass., 1906, v. 46, p. 756. 
Lewin, L., is quoted as making a number of general observations 
on the official (German) doses. 
(1) The basis for the determination of these maximum doses is 
furnished by toxicologic and clinical experiences. 
(2) The maximum limitations apply to the administration of 
medicaments to all parts where they may be absorbed into the fluids 
of the body (a) stomach, (b) rectum, (c) uterus, (d) thorax and 
abdomen, (e) hypodermatic injection, (f) intravenous injection, and 
(g) injection into the spinal canal. — (From Deut. Med. Wchnschr., 
1906.) Pharm. Zentralh., 1906, v. 47, p. 541. 
Herissey, H., notes that the Dutch Pharmacopoeia indicates the 
dose for an adult man, both initial and daily, and that physicians 
are not required to indicate excessive doses in their prescriptions. — 
J. de pharm. et de cliim., Pharm., 1906, v. 23, p. 478. 
Bokorny, Th. (Pfliigers Arch., 1906, x. Ill, pp. 341-375), main- 
tains that the question of toxicity is not so much that of the quantity 
of a poison necessary to kill a given quantity of living substance, but 
rather of the specific reaction of specific cells or tissues to specific 
poison under specific conditions. — Abstr. in Biochem. Centralbl., 
Leipz., 1906-7, v. 5, p. 201. 
Maurel, E. (Soc. de Biol., 26/V/06; v. 60, p. 909), says that- the 
physiologic study of any agent should always commence with the 
fixation of the minimal lethal dose (immediate and remote). It is 
necessary to fix these doses for each species of animal and for each 
method of administration. It is necessary also to report the quan- 
tity employed for each animal-kilogram. — Bull, des sc. pharmacol.. 
Par., 1906, v. 13 (Compt. rend, des soc. sav.), p. 188. 
