115 
The Ph. Brit. Committee of Reference in Pharmacy recommends 
the omission of the ferric-chloride test for acetanilide. Melting point 
might be 113° C. — Chem. & Drug., Lond., 1906, v. 69, p. 862. 
Ritter, John, calls attention to the fact that the pulvis acetanilidi 
compositus of the pharmacopoeia is a suitable substitute for any of 
the many acetanilide combinations on the market, which differ but 
little in composition. — J. Am. Med. Ass., 1906, v. 17, p. 683. 
Wilbert, M. I., considers the dose of acetanilide in the U. S. P. 
VIII, to be too high. — Am. J. Pharm., Phila., 1906, v. 78, p. 151. 
Mason, Harry B., in discussing legislation and patent medicines, 
suggests the advisability of prohibiting any proprietary headache 
powder or tablet from containing more than 3 grains of acetanilide, 
and of directing that the dose shall not exceed one at a time. — Proc. 
Am. Pharm. Ass., 1906, v. 51, p. 221. 
Puckner, W. A., calls attention to the fact that there is a general 
misapprehension that sodium bicarbonate renders acetanilide more 
soluble, whereas his experiments seem to show that it has no such 
effect. — J. Am. M. Ass., 1906, v. 17, p. 1206. 
Blackburn, A. E., relates a case of acetanilide poisoning from 
bromo-seltzer. — Ibid., v. 16, p. 1767. 
An answer to a correspondent asserts that bromo-seltzer, as found 
in the trade, contains: Potassium bromide, 10.53 parts; acetanilide, 
1.58 parts; caffeine, 1.20 parts, with sufficient diluent to make 100 
parts. — Ibid., v. 16, p. 151. 
A contributor to the “ Therapeutics " column quotes L. Williams, 
in the Clinical Journal, as saying that he considers acetanilide our 
most valuable and powerful antineuralgic next to morphine. He 
does not consider a slight cyanosis as necessarily alarming. — Ibid., 
v. 17, p. 1326. 
Goepp, R. -M., reports a case of acetanilide poisoning resulting 
from the long-continued use (eleven months) of acetanilide on an 
ulcer. There was great emaciation. Recovery followed the discon- 
tinuance of the drug. — Ibid., v. 17, pp. 359-361. 
Tyrrell, John Boyd, reports a case of acute acetanilide poisoning 
from the free use of acetanilide following the ingestion of other 
headache remedies. — Ibid., v. 16, p. 955. 
Herrick and Irons report a comprehensive study of a case of 
chronic acetanilide poisoning, with details regarding the urinary 
findings and some additional animal experiments. — Ibid., v. 16, pp. 
351-357. 
An editorial comments on chronic acetanilide poisoning. — Ibid., 
v. 16, p. 365. 
Fonteyne, A., gives a number of historical and pharmacologic 
references in addition to the details of his own researches on the 
effect of intravenous injections of acetanilide. — Arch, internat. de 
