132 
Riedel’s Berichte reports that, on slowly heating, salicylic acid 
melts quite uniformly at 157° C. ; on heating more rapidly it melts 
at from 157 to 158° C. — Riedel’s Berichte, Berlin, 1906, p. 22. 
Ohliger, Willard, reports salicylic acid which contained easily 
carbonizable impurities. — Proc. Michigan Pharm. Ass., 1906, p. 16. 
Franceschini, Francesco, presents a study of the absorption of sali- 
c}dic acid, as indicated by its elimination through the urine, after 
the external application of various preparations; hydroalcoholic 
solution, ointment with and without turpentine, methyl salicylate 
with olive oil. methyl salicylate, mesotan, mesotan with olive oil, 
and mesotan with turpentine. — Arch, di farmacol. sperim., 1906, v. 
5, pp. 539-547. 
Rodriguez Carracido, Jose (Vortrag, gehalten vor der Konigl. 
med. Akad. in Madrid, 4/1/06, p. 47), discusses salicylic acid in the 
role of an agent modifying organic oxidation. Eliminated as sali- 
cyluric acid, there is a saving in the amount of oxygen required to 
oxidize glycocol. * * * In every gramme of glvcocol which is 
paired with salicylic acid the organism is spared 622 milligrammes of 
oxygen. — Abstr. in Biochem. Centralbl., Leipz., 1906, v. 5, p. 131. 
Stockman, R. (Brit. M J., Nov. 24), states that there can be no 
reasonable doubt that compounds of salicylic acid, or those yielding 
it in the body, have a specific action against the poison of acute rheu- 
matism. This action is often too feeble to cut short an attack, 
and this is particularly true when the inflammation is seated in the 
fibrous tissues connected with the muscles and joints, or the valves of 
the heart. — J. Am. M. Ass., 1906, v. 47, p. 2124. 
Shoemaker, John V., condemns the use of salicvlic acid and all 
other coal-tar derivatives in the treatment of acute articular rheu- 
matism. — N. York M. J., 1906, v. 83, p. 378. 
Lafay, L., commenting on a laryngologist’s prescription for sali- 
cylic acid, takes up the general question of the solubility of salicylic 
acid and the advisability of the physician giving the pharmacist 
some hint as to the exact end sought to be attained through his 
prescription. — Bull, des sc. pharmacol., Paris, 1906, v. 13 (Compt. 
rend, des soc. sav.), pp. 126-127. 
Kionka, H., reports that his experiments appear to confirm the 
previously made observation that salicylic acid has a marked influence 
on biliary secretion. — Ztschr. f. exper. Path. u. Therap., 1906, v. 2, 
p. 15. 
Wilcox, Reynold Webb, recommends the use of salicylic acid in 
gall-stone disease and presents a formula for a combination which, 
in his hands, has proved efficient in a number of instances. — Trans. 
Am. Therap. Soc., 1906, pp. 114-117. 
Wiley, H. W., presents the general results of the investigations 
showing the effects of salicylic acid and salicylates upon digestion 
