161 
Barnard, H. E., reports that of 15 samples of black antimony ex- 
amined bnt 2 were pure antimony sulphide. All the others were 
almost entirely fraudulent. But 7 of the entire number contained 
any antimony sulphide whatever. — Rep. Indiana Bd. Health, 1906, 
pp. 367, 368. 
ANTIPYRINA. 
Gunn, Alexander, quotes Attfield on the use of the word “ Phena- 
zone " as follows : “ I brought this word before the Pharmacopoeia 
Committee on July 7, 1890. It was accepted and will be found in the 
‘ B. P. Additions,’ published in December. 1890. v In December, 
1891, it was suggested by Ernest Tauber (Berichte, v. 21, 3883) as a 
convenient short name for diphenylenazone. Other citations are: 
Loth, Meyer, jr. (Berichte, v. 26, 2238-2212, 1903). Zur Iventniss 
des Phenazons, abstracted in J. Chem. Soc. Beilstein, IV, Auflage, 
III. 1899, p. 1103; Diphenylazon, Phenazon C 12 H S X 2 . Briihl’s 
Chemie Sechsgliedern Heterocyclischen Svsteme, 1899. p. 779, Diben- 
zopyridazine, which is called phenazon C^HglC.,, and again on 
p. 801, etc. Gunn suggests that as phenazon is now so gener- 
ally used for diplien}denazone, it would appear advisable to drop 
the word as a synonym for the medicinal phenyl-dimethyl-iso-pyra- 
zolone and revert to antipyrine, quoting the U. S. P. VIII as fur- 
ther authority. — Pharm. J., Loud., 1906, v. 23, p. 6. 
Riedel's Berichte points out that the melting point of antipyrine is 
variously given as being from 105° to 113°. A pure preparation was 
found to melt uniformly at 111° C. In an air bath it required 
112° C. — Riedel's Berichte, Berl., 1906, p. 25. 
Lefeldt, Max, asserts that he was unable to obtain pyrazoloniun 
phenyldimethylicum having the melting point prescribed in the Ph. 
Germ. (113° C.), the melting point being from 110° to 111° C. — 
Ber. d. pharm. Gesellsch., Berl., 1906, v. 16, p. 311. 
Utz asserts that antipyrine melts at from 111° to 112°. — Apoth. 
Ztg., Berl., 1906, v. 21, p. 930. 
Fernan, Albert, reports finding one sample of antipyrine, melting 
point 106° C., decided coloration with solution of silver nitrate. — 
Ztschr. d. allgem. oestrr. Apoth.-Ver., 1906, v. 11, p. 79. 
Sperling, Friedrich, discusses the u Isonitroso reaction " of anti- 
pyrine as outlined in the Ph. Austr., and points out some of the short- 
comings and limitations of this test. — Ibid., v. H, pp. 51-52. 
Thornton, P. Leutharclt. gives some interesting figures, based on 
a yearly production of 100 tons, showing what is required to manu- 
facture antipyrine. The yield is given as 221,000 lbs. ; value. £38,889 
7s. 10d., or 3s. 5fd. per lb. — Chem. & Drug., Bond., v. 69, p. 169. 
11667— Bull 58—09 11 
