180 
Kohnstamm, Oscar, discusses the use of atropine in acute coryza, 
particularly as an abortive measure. — Therap. d. Gegenw., Berl., 1906, 
v. 47, pp. 526-527. 
Scrini (Bull. Commerc.. 1906, Xo. 1) recommends the use of 0.2 
to 0.5 per cent solutions of atropine in peanut oil or olive oil in the 
eye in place of aqueous solutions of the same alkaloid. — Pharm. Ztg.. 
Berl., 1906, v. 51, p. 301. 
Grube (Inaug.-Diss., Gottingen, 1905) reports a comparative study 
of several mydriatics. He concludes that atropine and eumydrin 
5 per cent paralyse accommodation always and fully, eumydrin 1 per 
cent and homatropine not without exception. The height of the 
paralysis lasts with atropine not quite so long as the mydriasis, but 
with the other medicaments quite as long; the full accommodation 
breadth (focal distance?) is restored with the appearance of normal 
pupil diameter. — Abstr. in Biocliem. Centralbl., Leipz., 1906-07, v. 5. 
p. 249. 
Lafon, Ch., points out that the continued use of atropine in the 
eye will, in certain cases, produce follicular conjunctivitis, that has 
been designated as “ atropine catarrh." — Bull. Soc. de pharm. de 
Bordeaux, 1906, v. 46, p. 16. 
Tyrrell, John Boyd, states that actute atropine poisoning is not 
uncommon from the use of atropine in the eye or from belladonna 
piaster, but he describes a possibly unique case of collapse, with other 
symptoms of poisoning, following the continued use of atropine in 
the eye. — X, York M. J., 1906, v. 84, pp. 273-274. 
Howe (Ophthalmology, 1906) discusses the effects of full and of 
minimum doses of atropine sulphate and of homatropine hydrobro- 
mide. — Biochem. Centralbl., Leipz., 1906-7, v. 5, p. 633. 
Drenkbabn (from Therap. Monatsh., Berlin, v. XIX, Xo. 1) sug- 
gests the greater or more extended use of atropine because of its 
power to relax the muscles and to hold them relaxed. — J. Am. M. 
Ass., Chicago, 1906, v. 46, p. 996. 
Bertozzi (Astenore) in the order of their comparative toxicity 
rates these substances as follows: Atropine sulphate, neutral=l; 
homatropine hydrobromate=1.21 ; methyl-atropine bromide=5.69 ; 
eumydrine=7.99. — Arch, di farmacol. sperim., Roma, 1906, v. 5, pp. 
123-133. 
Frazier, C. E., (Med. Arena) finds atropine, hypodermically, 
always indicated and seldom failing in post-partum haemorrhage. 
Felter adds a note on the efficacy of its combination with morphine. — 
Eclectic Med. J., Cincin., 1906, v. 66, p. 283. 
Bartlett. Clarence, discussing the dose of atropia, questions the 
accuracy of the statement that the twelfth of a grain has been given 
hypodermically without producing drug symptoms. The dose rec- 
ommended is one four-hundredths to one one-hundredtli of a grain 
