185 
the fact is recalled that tradition was departed from and the leaves 
abandoned in favor of the root, because more constant preparations 
would be obtained, the committee’s remarks give rise to strange re- 
flections. — Ibid., 861. 
Dohme, A. E. L., reports (Am. Druggist, X. Y., 1906, v. 19, p. 
268) the per cent of alkaloid found by seven reputable chemists, oper- 
ating upon the same samples of belladonna by the same process, as 
follows : 
A. B. C. D. E. F. G. 
Belladonna root 0. 58 0. 72 0. 49 0. 59 0. 56 0. 65 0. 61 
Belladonna leaf 0. 17 0. 33 0. 41 0. 32 0. 28 0. 24 0. 24 
Ext. belladonna leaf 1. 21 1. 03 1. 50 1. 04 1. 46 1. OS 
FI. ext. belladonna root- 0. 48 0. 37 0. 51 0. 42 0. 41 0. 46 0. 48 
Evans Sons Lescher and Webb examined a sample of dry autum- 
nal belladonna herb in which portions of the stem were present as 
well as leaves and fruit. The average alkaloidal content was 0.3d 
per cent by extraction with Prollius’s fluid. The stems yielded 0.16 
total alkaloid, the fruit 0.41 per cent, and the leaves 0.4 per cent. The 
herb yielded about 15 per cent extractive, which was of a brownish 
color and therefore valueless. — Analytical Xotes, for 1906, 1907, p. 8. 
Hankey, William T., found belladonna leaves to vary from 0.230 
per cent of mydriatic alkaloids to 0.516 per cent. He suggests using 
a larger amount of the menstruum to exhaust the drug. — Am. Drug- 
gist, X. Y., 1906, v. 49, p. 360. 
Vanclerkleed, Charles E., reports the assay of 5 lots of belladonna 
leaf which averaged 0.481 per cent of mydriatic alkaloids. All as- 
sayed higher than the required 0.35 per cent. — Proc. Pennsylvania 
Pharm. Ass., 1906, p. 122. 
The inspectors of pharmacies found tincture of belladonna with but 
0.62 per cent of dry extract. — J. de Pharm. d'Anvers, 1906, v. 62, 
p. 91. 
Francis, John M., says the average assay of 33 lots of belladonna 
leaf, representing 38.648 pounds, was 0.31 per cent; 8 were above 0.35 
per cent, 25 were below. The poorest was 0.23 per cent. — Proc. Am. 
Pharm. Ass., 1906, v. 54, p. 334. 
Patch, E. L., reports finding from 0.25 to 0.4 per cent of mydriatic 
alkaloids in the several samples of belladonna leaf examined. — Ibid., 
v. 54, p. 334. 
Ohliger, Willard, finds that most samples of the leaves assay a 
little below the requirement ; one sample, however, contained 0.67 
per cent of mydriatic alkaloids. The root averages about 0.5 per 
cent. — Proc. Michigan Pharm. Ass., 1906, p. 47. 
Graham, Willard, examined 3 samples of belladonna leaves. They 
contained, respectively, 0.40. 0.36. and 0.37 per cent of mydriatic alka- 
loids. — Proc, Pennsylvania Pharm. Ass,, 1906, p, 153. 
