201 
a half times less frequent. The chloride may be replaced by other 
salts, notably the lactate. The dose mentioned is, however, not suf- 
ficient to prevent the occurrence of the eruption when the injection 
exceeds 10 cc., and he purposes giving more than 1 gm. and prolong- 
ing the administration of the lime salt. — Compt. rend. Soc. de biol., 
Par., 1906, v. 60, pp. 279-282. 
An editorial calls attention to the use of calcium chloride prelimi- 
nary to operation after it had been noticed that a needle prick was 
followed by continued bleeding. There was no excessive haemor- 
rhage at the operation. — X. York M. J., 1906, v. 83. p. 12. 
An editorial calls attention to the advantages of calcium chloride 
in haemorrhage by its increasing the coagulability of the blood. — 
J. Am. M. Ass., 1906, v. 17, p. 11. 
Chantemesse, A. (Presse. Med., Par., v. 11, Xo. 16), recommends 
the use of calcium chloride for preventing haemorrhage in typhoid 
fever. — Ibid., v. 16, p. 1103. 
Dixon, IV. E., (Lancet, LoncL, Mar. 21, 1906) believes that calcium 
chloride is the best remedy for internal haemorrhage. — Ibid., v. 16, 
p. 1212. 
Murray, Charles, finds that in regard to fibrinogen the relation of 
calcium salts to heat-coagulation is very different from their relations 
to ferment-coagulation. — Biocliem. J., Liverpool, 1906, v. 1. pp. 
167-171. 
Evans, Herbert I., calls attention to the fact that calcium chloride 
has been recommended of late for a variety of conditions, and states 
that he has treated a case of pleurisy with it successfully. — Brit. M. 
J., Lond., 1906, v. 1, p. 1377. 
Coe, J. TV., discusses the use of calcium chloride in haemorrhage 
and reports the successful treatment of haemophilia and purpuric con- 
ditions with calcium lactate. He calls attention to the belief that 
the continued use of calcium chloride increases the time for coagula- 
tion of the blood, and questions whether the action of the lactate dif- 
fers from that of the chloride. — J. Am. M. Ass., 1906, v. 47, pp. 
1090-1093. 
Additional references to the use of calcium chloride are to be found 
in the Index Medicus and the J. Am. M. Ass. 
CALCII HYPOPHOSPHIS. 
Patch, E. L., reports finding calcium hypophosphite which con- 
tained a large excess of sulphate. — Proc. Am. Pharm. Ass., 1906, v. 
54, p. 334. 
Caspari, Chas. E., reports two samples examined : OneU. S. P. ; one 
. contained soluble phosphates. — Proc. Missouri Pharm. Ass., 1906, 
p. 101. 
