228 
CINCHONA. 
Mittelbach, Wm., raises the question as to whether there ought to 
be two barks recognized. 
Whelpley, H. M., explains that these two specific plants are men- 
tioned because they are the two reliable barks most frequently found 
in commerce. 
Brandenberger, A., maintains that the official bark should be either 
the “ red ” or the u pale." 
Hemm, Francis, agrees with Mittelbach and thinks the color does 
not cut any figure. He suggests a recommendation to the Committee 
of Revision that there be but one, which should contain approxi- 
mately 5 per cent of alkaloids. — Proc. Missouri Pharm. Ass., 1906, 
p. 35. 
An unsigned critique of the Ph. Adi. IV notes the requirement of 
not less than 0.6 per cent of alkaloids. — Chem. & Drug., Lonch, 1906, 
v. 68, p. 828. 
Gehe & Co. discuss the economic conditions prevailing in the cin- 
chona market. They give the amount of bark exported from Java 
during the years 1902 to 1905, inclusive, and point out that the average 
content of quinine during this period has been well above 5 per cent ; 
5.49 per cent in 1905. They also point out that American barks have 
practically lost interest and that, apart from a few of the South 
European countries, there is practically no demand, though the true 
flat Calisaya, as well as the Guayaquil, Huanoco, and Loxa barks are 
to be found in regular supplies. — Handels-Ber., Gehe & Co., 1906, 
pp. 23-25. 
An editorial calls attention to the fact that the supplies of bark 
offered at auction (Amsterdam and London) during 1905 were about 
3,100,000 pounds more than the average of the preceding three 
years. — Brit. & Col. Druggist, Lond., 1906, v. 49, p. 90. 
Gerock, J. E., discusses the market conditions and the production 
of cinchona. He does not believe that there has been any marked 
decrease in the amount of cinchona and quinine consumed, despite 
the evident reduction in the amount imported into the United 
States. — J. d. Pharm. v. Elsass-Lothr., 1906, v. 33, pp. 38-41. 
England, J. W., exhibited a sample of powdered Java cinchona 
containing 10 to 12 per cent of alkaloid estimated as quinine sulphate. 
He said that fully 95 per cent of the cinchona bark on the market is 
derived from the cultivated cinchona trees in Java and that the 
cinchona market of the world has changed from London to Amster- 
dam. * * * It is not unusual for the alkaloid yield to be equiva- 
lent to 12 or 13 per cent of quinine sulphate. — Am. J. Pharm., 
Phila., 1906, v. 78. p. 99. 
Goris and Reimers (Trav. Lab. Mat. med. Ecol. super. Pharm., 
Par.) point out that Cinchona rohusta Trimen is a collective name 
