237 
I 
extractive (nonvolatile), 1.53 per cent; alcohol extractive, 12.8 per 
bent. — Lab. Rep., S. K. & F., 190G, pp. 35, 36. 
Weigel points out that the Ph. Nell, requirement for Cinnamomum 
veylaniciim is that the ash content may vary from 4 to 8 per cent. — 
Pharm. Zentralh., 1906, v. 4T, p. 400. 
COCA. 
Levy, N. (Siidd. Apoth. Ztg.), discusses the cultivation of Ery- 
throxylon coca in the mountainous regions of Peru and presents some 
information on the distribution and uses of the drug. — J. de pharm. 
d Anvers, 1906, v. 62, pp. 106, 107. 
Winkler, Hans, describes the cultivation of Erythroxylon coca 
Lam. in Java and gives an outline of the history of the plant and its 
cultivation and use by the Incas of Peru. — Der Tropenpflanzer, 1906, 
v. 10, pp. 69-81. 
Francis, John M., asserts that Huanuco coca has the best aroma 
and contains more cocaine and less isotropyl-cocaine. The assay of 
15 lots varied from 0.32 to 0.83 per cent, the average being 0.69 per 
cent. — Proc. Am. Pharm. Ass., 1906, v. 54, p. 336. 
The Ph. Brit. Committee of Reference in Pharmacy report on 
coca leaves savs: Restrict to the Bolivian variety of South American 
«y «y 
I or Ceylon growth. For galenical preparations use leaves with 0.5 
per cent of total alkaloids. — Chem. & Drug., Lond., 1906, v. 69, p. 863. 
Herting, Otto, discusses the official requirements for the leaves of 
Erythroxylon coca and suggests, in place of the official assay process, 
a gravimetric method based on the deJong modification of Keller’s 
method. — D.-A. Apoth. Ztg., N. Y., 1906-7, v. 27, p. 1. 
deJong, A. W. Iv., (Rec. trav. chim. Pays-Bas, v. 25, pp. 233-237) 
discusses the behavior of the alkaloids in coca leaves and points out 
that with the dying of the leaf the alkaloids disappear slowly, though 
not entirelv. He also discusses the change from einnamvl-cocaine to 
benzoyl-cocaine with the growth of the leaves; discusses the extrac- 
tion of the leaves of coca ; and outlines a method that he believes to 
be economical and satisfactory. — Biochem. Centralbl., Leipz., 1906-7, 
v. 5, p. 909. 
Puckner, W. A., reviews some of the recent literature relating to 
the assay of coca, and points out that the use of ether instead of 
chloroform in the final extraction of the U. S. P. VIII process, is 
done for the purpose of rejecting alkaloids other than cocaine. — 
Pharm. Rev., Milwaukee, 1906, v. 24, p. 236. 
Puckner, W. A., reviews some of the recent literature relating 
to the assay of coca, and points out that the use of ether instead of 
tube percolator used, to avoid transfer of the ethereal liquid from 
vessel to vessel. — Am. J. Pharm., Phila., 1906, v. 78. p. 455. 
