240 
profession it is difficult to form a conclusive opinion. — Therapist, 
Lonch. 1906. v. 16. pp. 121. 122. 137, 138, 147, 148. 
Reichmuth (Zeitsclir. f. Augenheilk., v. 16, p. 3) presents ob- 
servations on the structural damage done bv the several local an- 
{.esthetics — cocaine, holocaine. beta-eucaine. tropacocaine. acoin. aly- 
pin. — Biochem. Centralbl.. Leipz.. 1906-7. v. 5. p. 809. 
Lawen. A., presents the results of the comparative study of the 
local action of cocaine, holocaine. alypin. and stovaine on motor 
nerve trunks (Arch. f. exper. Path.. 1906. v. 56. p. 138). — Ibid.. 
v. 5, p. 909. 
TTintersteiner (Wien. klin. TTochenschr.. 1906) discusses the use 
and the applicability of cocaine and its substitutes in ophthalmology, 
and concludes that cocaine is superior to all of the several substitutes 
so far offered. — Ibid., p. 909. 
Scrini (Bull. Commerc.. 1906, No. 1) recommends the use of 2 per 
cent solutions of cocaine (alkaloid) in peanut or olive oil for use in 
the eye in place of acpieous solutions of the salts of cocaine. — Pliarm. 
Ztg., Berk, 1906, v. 51, p. 301. 
Moore. T. TY, reports a case of idiosyncrasy to the use of cocaine 
in the eye; the lids became very much swollen, and when a single 
drop of a 4 per cent solution of cocaine was dropped into the eye on 
a subsecpient occasion the same symptoms were seen in a milder 
form. — J. Am. M. Ass., 1906. v. 47. p. 1486. 
Pruyn, C. P. (Dent. Rev.), thinks the septic troubles often fol- 
lowing the use of cocaine in dental surgery are to be attributed to 
the infection and not to the cocaine. — Dental Cosmos, Phila., 1906. 
a~. 48, p. 967. 
Touehard. F., (UOdontol, Paris, Sept. 15, 1906) discusses the 
technique of cocaine injections in dental surgery, and is inclined to 
use it even for very minor operations. — Ibid., pp. 1264-1267. 
Apropos of ToucharcTs article, an editorial argues, on physio- 
logical, moral, and ethical grounds, against *’ cocainizing humanity 
for everv disagreeable sensation from which the hvsterical or 
morally weak desire to escape.* - — Ibid., pp. 1256-1261. 
Scliieffelin, TCm. J.. discusses the constitution, synthesis, and the 
safeguarding the sale of cocaine. He asserts that the annual con- 
sumption of cocaine in the United States is between 100.000 and 
120,000 ounces, and that, judging from the decline of the sale in a 
locality where a strict cocaine law is enacted and enforced, at least 
20 per cent is used for indulgence. — Abstract in Am. Druggist. X. Y.. 
1906, v. 48, pp. 177. 178. 
The editor of u Xotes and Queries ** estimates the consumption of 
cocaine in the United States, based upon custom-house figures, as 
156.032 ounces in 1903. 150.632 ounces in 1904. and quotes TT. J. 
Schieffelin’s estimate at 100.000 to 120.000 ounces annuallv. (See 
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