252 
Le Ferre. R. E.. states that he has used creosote in the treatment 
of whooping cough, in which it allays irritation, facilitates the expul- 
sion of mucus, and possibly acts as an antiseptic. — Ibid v. 83, p. 7(14. 
Porter. W.. states that creosote is of minor importance in the treat- 
ment of tuberculosis and that larger doses are not indicated. — J. Am. 
M. Ass.. 1906. v. 46. p. 1574. 
Van den Berg. William H.. asserts that creosote, or its derivative 
guaiacol. is still useful in a number of cases as an intestinal anti- 
septic. — Trans. Am. Inst. Homoeop.. 1906. 62d sess.. p. 397. 
CRESOL. 
Riedel's Berichte presents an exhaustive study on commercial cresol 
with the conclusion that the Ph. Germ, should require that cresol 
contain a specified quantity of a fraction that will distill between 
195° and 205° C., as it is in this particular fraction that the more 
valuable cresols are found. — Riedel's Berichte. Berl., 1906. pp. 40-43. 
Dreyfus. W. E.. reviews the U. S. P. VIII requirements for cresol 
and savs. ** on the whole I find that cresol has not been thoroughlv 
studied by the member of the committee having this special subject 
in charge. " — Drug. Cire. & Client. Gaz.. X. Y.. 1906. v. 50. p. 296. 
Vanderkleed. Charles E.. reports difficulty in obtaining cresol that 
would answer the U. S. P. requirements as regards absence of 
phenol. — Proc. Pennsylvania Pharrn. Ass.. 1906. p. 122. 
Graham. Willard, asserts that considerable trouble was experienced 
in obtaining cresol which would answer to the tests laid down in the 
U. S. P. — Ibid ., p. 153. 
Patch. E. L.. reports that three out of six samples of cresol ex- 
amined answered the pharmacopoeial requirements. — Proc. Am. 
Pharrn. Ass.. 1906, v. 54. p. 336. 
Francis, John AL, asserts that it is almost impossible to find a 
U. S. P. product. — Ibid., p. 336. 
Vanderkleed. Charles E.. points out that great care is necessary in 
applying the test for phenol in cresol. If more- than the prescribed 
quantity of glycerin is used, even absolutely pure cresol will not 
entirely separate out. thus leading to the wrong conclusion that 
phenol is present. — Proc. Pennsylvania Pharrn. Ass., 1906. p. 133. 
Coblentz. Virgil, urges great care in the application of this test 
and calls attention to its lack of delicacy, quoting At. F. E. Dodge, of 
the Barrett Alfg. Co. — Apothecary. Bost.. 1906, v. 18. p. 911. 
La Wall and Cook report the results of experiments to determine 
the quality of the cresol on the market, and suggest that a slight 
modification of the official formula for compound solution of cresol, 
as outlined by them, produces a more satisfactory preparation. — Am. 
J. Pharrn. Phila., 1906. v. 78. pp. 169-172. 
