260 
Hatcher, Robert. A., discusses the pharmacology of digitalis and 
some of the digitalis principles. — J. Am. M. Ass., 1906, v. 47, pp. 
2059-2061. 
Cloetta and Fischer discuss the behavior of digit oxin in the organ- 
ism and report a series of experiments to determine the distribution 
of digitoxin in various organs and parts of the body. (From Ztschr. 
f. physiol. Chem. v. 47.) — Biochem. Centralbl., Leipz., 1906-7, v. 77, 
p. 1369. 
von den Velden, R., reports experiments with digitalis substances, 
digitoxin and convallamarin, to determine their action on the depres- 
sor nerve. — Arch. f. exper. Path. u. Pharmakol. Leipz., 1906, v. 55, 
pp. 223-239. 
Haynes, G. S., considers digitalis less efficient as a cardiac stimu- 
lant (that is, a drug which increases the cardiac output per beat) 
than squill, in that it has not the same effect in increasing the energy 
of contraction of the heart, — Biochem. J., Liverpool, 1906, v. 1. pp. 
62-87. 
An editorial discusses the results of Hayne’s experiments, published 
in the second number of the Bio-Chemical Journal, in which the 
actions of digitalis, squills, and strophanthus were compared. Haynes 
is quoted as recommending a more extended use of squill in cardiac 
disease, but attention is called to the greater vaso-constriction and 
the more pronounced action on the gastro-intestinal tract. — Brit. 
M. J., Lond., 1906, v. 1, p. 1494. 
Filippi, Eduardo, undertook a research to determine whether there 
is indeed an analogy between digitalis and barium. He arrives at 
the general conclusion that the chloride of barium is a myocardial 
poison. The paper gives eight figures of cardiograms and a tabu- 
lated statement of pressure variations, He does not share the enthu- 
siasm of those who have clinically adopted BaCL as a substitute for 
digitalis. — Arch, di farmacol. sperim., 1906, v. 5, pp. 103-122. 
Schmidt, Ad., (Berl. kiln. Wchnschr. v. 43, No. 13) states that 
digitalis is more useful than all other measures combined for certain 
forms of gastro-intestinal troubles. — J. Am. M. Ass., 1906, v. 47, 
p. 241. 
Reilly, T. F., calls attention to the intravenous use of digitalis 
preparations in Germany, while this method has not thus far made 
progress here. — Ibid ., v. 47, p. 649. 
Goepp, R. Max, discusses the action of digitalis, discredits the opin- 
ion that it is cumulative, and has found digitalin, German, Merck, 
an efficient remedy in doses of from one-thirtieth to one-eio-hth 
grain. — Merck’s Arch., N. Y., 1906, v. 8, pp. 10-12. 
Cloetta, M., (Mlinchen med. Wchnschr., v. 53, No. 47) states that 
the cumulative action of digitalis leaves is not seen with the fresh 
