GUAIACOLIS CARBONAS. 
Fernan, Albert, found a sample of guaiacol carbonate with a yel- 
low coloration that had a melting point of 89° C., 22.86 per cent meth- 
oxyl. — Ztschr. cl. allg. osterr. Apoth.-Ver. Wien, 1906, v. 44, p. 79. 
Garceau, Edgar, recommends the internal use of guaiacol carbonate 
in tuberculosis of the urinary tract in women, in connection with in- 
jections of corrosive sublimate into the bladder according to the 
Guyon method — J. Am. M. Ass., 1906, v. 47, p. 1441. 
GUAIACUM. 
Naylor, W. A. H., reviews the chemistry of guaiacum and suggests 
that the U. S. P. test with cupric acetate be made to read : “ When 
shaken with an equal volume of an aqueous solution of cupric acetate 
(1-10) the supernatant solution should not be colored green.” The 
U. S. P. determination of the acid number is described as being un- 
satisfactory, inasmuch as the end reaction is indefinite, and a small 
error in reading off the volume of alkali required is the cause of a 
large error in the result. — Year Book of Pharmacy, 1906, p. 213. 
(See also Pharm. J., Lond., 1906, v. 23, p. 76.) 
The Ph. Brit. Committee of Reference in Pharmacy report on 
guaiacum says not less than 90 per cent soluble in alcohol, and not 
more than 3 per cent of ash. Experiment on the acid value. — Chem. 
& Drug., Bond., 1906, v. 69, p. 863. 
Ricnter, Paul, makes a contribution to the knowledge of the com- 
position of guaiac resin. He discusses the literature and reports 
his findings in connection with the dry distillation of guaiac resin 
and of guaiac acid; also the nature of guaiac acid and its relation 
to guaiac blue ; the nature of guaiac blue. — Arch. d. Pharm., Berl., 
1906, v. 244, pp. 90-119. 
Francis, John M., found 90 per cent of the commercial samples of 
guaiacum to contain 85 per cent or more of alcohol-soluble resin; 70 
per cent contained over 96 per cent ; and less than 10 per cent fell 
below the U. S. P specifications. — Bull. Pharm., Detroit, 1906, v. 
20, p. 54. 
Hankey, William T, asserts that the great majority of the samples 
of guaiac examined by him exceeded the 15 per cent limit of insolu- 
ble matter permitted by the U. S. P. VIII, some samples running 
as high as 29 per cent insoluble matter, while others ran as low as 
2.25 per cent. He found the ash to range from 0.50 to 6.40 per cent. 
He also calls attention to the difficulty of determining the acid num- 
ber. — Am. Druggist, N. Y., 1906, v. 49, p. 361. 
Roethtisberger, P. (Arch. f. Verdauungs Krank., Berl., v. 12, No. 
3), states that C. W. Huf eland has highly recommended the use of 
11667— Bull. 58—09 20 
