308 
Stephens commends hedeoma strongly for the relief of pruritis and 
eczematous eruptions. He finds a 1 per cent cerate useful also in irri- 
tation of the Schneiderian membrane. — Eclectic Med. J., Cincin., 
1906, v. 66, p. 316. 
HEXAMETHYLENAMINA. 
Francis, John M., thinks hexamethylenamina is easily made but 
extremely difficult to purify ; the identity and purity tests are ample ; 
the identity once established the pharmacist may well rely upon his 
sense of smell, as when this substance is refined enough to be devoid 
of odor it will most probably meet all purity tests. — Bull. Pharm., 
Detroit, 1906, v. 20, p. 54. 
Eastenbau, M., (Rev. Scientif. Professional) outlines a method for 
preparing hexamethylene-tetramine b} T simply combining the neces- 
sary quantities of a 40 per cent solution of formaldehyde and aqua 
ammonia. For purifying, the resulting crystals are dissolved in the 
smallest possible quantity of boiling alcohol, which is then allowed to 
cool slowly. The resulting crystals are to be dried on filter paper. — 
J. de pharm. d 'Anvers., 1906, v. 62, p. 724. 
Kahn, Joseph, outlines several readily applied tests for the iden- 
tity of hexamethylenamine. — Am. Druggist, N: Y., 1906, v. 49, p. 6. 
Ischidzu and Inouve have studied the nature of the decomposition 
products of hexamethylenamina and the influence of various acids 
and of Japanese sake on hexamethylenamina. They conclude that 
acids readily decompose hexamethylenamina into formaldelryde, car- 
bon dioxide, and methylamine. Hexamethylenamina is more stable 
in alkaline solutions than in neutral, boiling water will liberate 
formaldehyde. — J. Pharm. Soc. Japan, 1906, p. 1. 
Mohr, F., quotes Guiard, who (Ann. d. mal. d. org. genito-urin.) 
refers to a Swiss specimen of hexamethylene-tetramine so manifestly j 
inferior as to be positively dangerous. — Bull, des sc. pharmacol. Par., 
1906, v. 13, p. 387. 
Stimson, Edward P., calls attention to the discrepancy between 
the price of hexamethylenamine as given in a current price list and 
that of some of the proprietary preparations. — J. Am. M. Ass., 1906, 
v. 47, p. 2024. 
Thursfield, H., (Brit. M. J., Fond., Apr. 21) recommends urotropin 
in bacteriuria. — Ibid., v. 46, p. 1566. 
Coleman, W., (Clin. Rev.) reports having observed gastro-intes- 
tinal disturbances after 1 gm. doses of urotropin. He also reports 
other secondary effects. — Jahresber. ii. Tier. Chem., Wiesb., 1906, 
1907, v. 36, p. 794. 
Shattuck, Frederick C., says that for the past eight years his j 
typhoid patients have had 7 to 10 grains of urotropin thrice daily, i 
two successive days of each week, until convalescence was complete. 
