321 
McMillen combines lupulin and hydrastis in digestive wrongs in 
the small intestines, with loss of appetite and disturbed sleep. The 
hydrastis is a tonic to all mucous membranes, and because of this 
action it is one of our best remedies to influence the sympathetic 
system. These nerves are largely distributed to mucous surfaces. It 
is a harmless remedy, but a good one, and should have the preference 
over the strong poisons as a nerve tonic. — Eclectic Med. J., Cincin., 
1906, v. 66, p. 161. 
Leming, William, (Modern Eclecticism) commends hydrastis when 
there are chronic catarrhal and congestive conditions of mucous mem- 
branes, with muscular a tonicity and yellow-coated tongue, generally 
moist and of natural or increased redness. — Ibid., v. 66, p. 441. 
HYOSCINiE HYDROBROMIDUM. 
Francis, John M., refers to the controversy over the supposed 
identity of hyoscine and scopolamine and the added confusion made 
by Cushny’s announcement that the scopolamine of commerce con- 
tains both lsevo- and dextro-rotatory constituents which probably 
differ in therapeutic activity. — Bull. Pharm., Detroit, 1906, v. 20, 
p. 55. 
See also under Scopolamina. 
HYOSCYAMINJE HYDROBROMIDUM. 
Francis, John M., referring to identity tests thinks that the pro- 
duction and preparation of the chloraurates, suitable for determining 
melting points, is a matter requiring considerable skill and practice, 
and doubts if many busy pharmacists will care to attempt it. The 
therapeutic action of the two closely related alkaloids is similar but 
not identical. — Bull. Pharm., Detroit, 1906, v. 20, p. 56. 
French, J. M.. says, as to the details of the action of hyoscyamine, 
there is much difference of statement by different observers, due, 
very probably, to the great difficulty of procuring pure hyoscyamine, 
and the fact that many of the specimens used are contaminated with 
atropine, — Merck’s Arch., N. Y., 1906. v. 8, pp. 35-40. 
HYOSCYAMUS. 
Henkel. Alice, mentions Hyoscyamus niger L., commonly known 
as hvoscyamus, henbane, hog’s-bean, and insane-root, as having been 
sparingly naturalized from Europe. Found in waste places from 
Nova Scotia to Ontario, New York, and Michigan. — Bui. Bur. Plant 
Ind., U. S. Dept. Agric., 1906, No. 89, p. 38. 
Rusby, H. H,, asserts that hardly any hyoscyamus comes to New 
York which is second-year growth, as the U. S. P. VIII directs. — 
Proc. Am. Pharm. Ass., 1906, v. 54, p. 338. 
11667— Bull. 58—09 21 
