366 
case morphine may be supposed to act as a paralyzer of the vasomotor 
system. — X. York M. J., 1906, v. 83, p. 703. 
Le Boutillier (Ann. Surg., Brooklyn, July) advises the subcuta- 
neous injection of morphine before the anaesthesia has passed when 
there is a probability that there would be much pain following the 
operation, the morphine being repeated often enough to keep the 
patient comfortable. — J. Am. M. Ass., 1906, v. 47, p. 461. 
Gonnermann, M., reviews the literature relating to the behavior of 
morphine to various enzymes and intestinal bacteria and records 
some experiments on the influence of animal and plant enzymes on 
morphine. The animal enzymes are practically without influence on 
morphine. — Apoth. Ztg. Berl., 1906, v. 21, p. 998. 
Felter, H. W., commenting on C. E. Frazier’s use of atropine in 
post-partum haemorrhage, adds a note on the value of morphine 
and atropine in profuse haemorrhages generally. — Eclectic Med. J., » 
Cincin., 1906, v. 66, p. 283. 
Wells, G. Harlan, finds morphine an indispensable remedy in 
severe cases of cardiac weakness associated with the distressing 
dyspnoea and insomnia which so often accompany extreme degrees I 
of cardiac dilatation. The first dose should be small and given hypo- 
dermically. It is contraindicated in fatty degeneration and where 
advanced renal lesion exists. The best results from its use are ob- 
tained in mitral disease. — Hahneman Month., Phila., 1906, v. 41, 
p. 262. 
Additional references on the use of morphine will be found in the 
Index Medicus and the J. Am. M. Ass. 
NOX OFFICIAL COMPOUNDS. 
An abstract from a German patent specification outlines the pro- 
duction of acetyl derivatives of morphine. — Chem. Repert, Cothen. 
1906, v. 30, p. 338. 
The Ph. Austr., VIII, in a footnote, points out that “Morphinum 
diacetylicum ” occurs in trade as “ heroin.” 
Magnanimi, R. (Studi Sassaresi, V. 4, pp. 30—41), reports experi- 
ments on the toxic properties of some of the derivatives of morphine 
(dionin, heroin, peronin). — Jahresb. u. Tier. Chem. for 1906, Wiesb., 
1907, v. 36, p. 794. 
See also under Diacetyl-morphine. 
MOSCHUS. 
Schimmel & Co., review a report by Alexander Hosie, consul-gen- 
eral at Chengtu, who gives some interesting information on the musk 
trade. They also report an exhaustive study of the composition of 
