419 
Baird, J. W., reports two samples examined in 1904, one adul- 
terated. — Proc. Massachusetts Pharm. Ass., 1906, p. 59. 
Dunning, H. A. B., asserts that a tincture of opium not deficient in 
strength may be made by mixing 100 gm. powdered opium with 50 
gm. calcium phosphate, pumice, or other suitable agent and percolat- 
ing with dilute alcohol (1,000 c. c.), collect, percolate, set aside, and 
then exhaust the opium with water. — Proc. Am. Pharm. Ass., 1906, 
v. 54, p. 445. 
Cline, R. R. D., suggests that in making tincture of opium the pow- 
dered opium be first mixed with sharp, clean, dry sand, previously 
sterilized and percolated with petroleum benzin, to free it from the 
odorous and otherwise objectionable principles. The benzin is subse- 
quently evaporated and the resulting drug exhausted in the usual 
way. — Proc. Texas Pharm. Ass., 1906, v. IT. 
Dunning, H. A. B., recommends the use of powdered paper in mak- 
ing tincture of opium, and asserts that a mixture of paper and opium 
can readily be extracted by percolation. — Proc. Am. Pharm. Ass., 
1906, v. 54* p. 485. 
Ladd, E. F., points out that laudanum has been found to vary in 
strength from 25 per cent to 116 per cent of the official standard of 
the United States Pharmacopoeia. — Rep. North Dakota Agric. 
Exper. Stat., 1906, Part II, p. 36. 
Sayre, L. E., reports that 11 samples of tincture of opium examined 
varied from 0.82 to 1.53 per cent of morphine. — Bull Kansas Bd. 
Health, 1906, v. 2, p. 176. 
The revisors of pharmacies in Wurtemberg, Germany, found 7 
samples of tincture of opium to be deficient in morphine, while four 
additional samples, barely complied with the requirements. — Pharm. 
Zentralli., 1906, v. 47, p. 650. 
Fernan, Albert, found a sample of tincture of opium containing 
0.25 per cent of morphine with 4.32 per cent of extract. — Ztschr. d. 
allg. osterr., Apoth.-Ver., Wien, 1906, v. 44, p. 80. 
Kriier, Hero, points out that the tincture of opium of the Pli. 
Germ. IV, when cooled to 10° C. becomes cloudy and frequently, at 
least, does not become perfectly transparent on rewarming. His 
experiments indicate this to be due to extracted gums. — Pharm. Ztg., 
Berl., 1906, v. 51, p. 1104. 
Wetterstroem, Theo. D., reports the results of a comparsion of the 
U. S. P. VII, and U. S. P. VIII, requirements for morphine in tinc- 
ture of opium. Presents the results of his experiments in the form of 
a table. — Proc. Am. Pharm. Ass., 1906, v. 54. pp. 431, 432. 
The Ph. Brit. Committee of Reference in Pharmacy concludes that 
the assay process for tincture of opium requires improvement, and 
should be adapted to the latter preparation. — Chem. & Drug., Lond., 
1906, v. 69, p. 865. 
