428 
He asserts that the U. S. P. VIII ointment is less sightly and 
generally less satisfactory than the corresponding preparation of 
the U. S. P. 1890. — Ibicl., v. 50, p. 160. 
Hommel, P. E., finds this ointment unsatisfactory in the summer, 
«- j 
as it liquefies; he wonders why paraffin was not added to give it 
consistency, as in the boric acid ointment. He suggests a formula 
with yellow wax and yellow petrolatum. — Proc. Xew Jersey Pliarm. 
Ass., 1906, p. 108. 
Blyth, M. Winter, presents a very interesting discussion on the 
standardization of disinfectants; he recommends the use of milk, the 
composition of which may be made exactly to represent, with regard 
to its influence on germicidal action, an equal weight of solid foecal 
matter. — J. Soc. Chem. Ind., Bond., 1906, v. 25, pp. 1183-1193. 
See also a paper by R. Tanner Hewlett, who experimented with 
B. typhosus in broth culture, using phenol, cyllin. and kerol. — 
Pharm. J., Bond., 1906, v. 23, pp. 69, 70. 
Meyer, Beo B., calls attention to the dangers of weak solutions of 
phenol when used as surgical dressing and cites 21 cases of greater 
or less injury resulting from its use in this way. — X. York M. J., 
1906, y. 84, p. 598. 
PHENOLPHTHALEIN. 
Kastle, J. H., reports a study of the conduct of phenolphthalein 
in the animal organism, the conduct of other phtlialeins in the ani- 
mal organism, and the action of ferments on phenolphthalein. — 
Bull. Hyg. Bab., U. S. P. H. & M.-H. S., Xo. 26, pp. 23-29. 
Brasch, G., (Ztsclir. f. Med. Beamte, Berl., 1906, XIX, 450— L52 ) 
discusses the use of phenolphthalein as a laxatiye with remarks on 
the introduction of new remedies. — Reference from Index Med., 1906, 
p. 984. 
Wilcox, R. W., recommends the use of phenolphthalein in the treat- 
ment of gallstone disease. — J. Am. M. Ass., 1906, y. 47, p. 348. 
Yon Best (Ztsclir. Med. Beamte, 1906) reports a case of untoward 
effect from the use of purgen, a proprietary preparation containing 
phenolphthalein. Two tablets, the advertised medium dose, in ad- 
dition to free purgation caused uneasiness, flushed face, difficulty in 
breathing, palpitation, and rapid pulse. The general condition im- 
proved in the course of several hours, but the accompanying colic- 
like pain did not disappear until the following day. — Jahresb. d. 
Pharm., 1906, Gotting, 1907, v. 41, p. 258. 
Brasch, G., (Ztsclir. Med. Beamte, 1906) considers phenolphtha- 
lein to be an excellent laxative in doses of from 0.05 to 0.1 gm. for 
children and 0.1 to 0.2 for adults; in obstinate cases of constipation 
0.3 to 0.5 gm. may be given without fear of secondary complica- 
tions. — Ibid., v. 41, p. 258. 
