432 
PILOCARPUS. 
Weigel, G., calls renewed attention to the substitute for Paraguay 
jaborandi that appeared in Marseille, and asserts that these leaves 
have been offered on the drug market under the name “ Feuilles de 
Bois d’lnde.” He points out that “ Bois d* Inde ” is a designation 
that is applied in France to the wood of Ilcematoxylon campecliia- 
num L ., a tree indigenous to Central America and the West India 
Islands. — Pharm. Zentralh., 1906, v. 47, p. 891. 
Moureau, Ch., (J. de pharm et de chim., 1906) reviews the work 
done by Jowett, who says that javorin of Hannack and Meyer is 
only a mixture of pilocarpine, pilocarpidine, and isopilocarpine.— 
Pharm. Ztg., Berl., 1906, v. 51, p. 832. 
Evans Sons Lescher and Webb, point out that two samples of the 
P. micro phyllus variety of jaborandi leaves gave 0.765 and 0.783 per 
cent of alkaloid, respectively. They have not been able to obtain 
supplies of the official variety. — Analytical Notes for 1906, E., L. & 
W., Lond., 1907, p. 21. 
The Ph. Brit. Committee of Reference in Pharmacy report on 
jaborandi says, if retained, Pilocarpus micropliyllus should be sub- 
stituted for the present official variety and the galenical prepara- 
tion standardized; leaves to give 0.5 to 0.75 per cent total alkaloid. — 
Chem. & Drug., Lond., 1906, v. 69, p. 864. 
Caesar and Loretz suggest the estimation of the moisture content 
of jaborandi, and outline a method for determining the alkaloids 
present, — Geschaft-Ber., von Caesar & Loretz, in Halle a. S., 1906, 
pp. 103, 104. 
Puckner, W. A., reviews some of the recent literature, relating to 
the assay of pilocarpus, and points out that the U. S. P. VIII 
method is satisfactory in that it avoids the use of aliquot parts. — 
Pharm. Rev., Milwaukee, 1906, v. 24, pp. 271, 272. 
Lyons, A. B., reports that but 4 of the 12 replies received indicated 
that the U. S. P. VIII standard for fluid extract of pilocarpus is 
satisfactory.. — Proc. Am. Pharm. Ass., 1906, v. 54, p. 437. 
Gordin, H. M., considers the method for the assay of the fluid ex- 
tract unnecessarily complicated, and suggests a simpler and quicker 
one, using his separatory funnels. — Ibid., v. 54, p. 380. See also 
Am. J. Pharm., Phila., 1906, v. 78, pp. 457-462. 
Puckner, W. A., points out that the sand method prescribed in case 
of fluid extract of pilocarpus is antiquated ; a method similar to that 
for fluid extract of belladonna gives good results and is more expe- 
ditious. — Proc. Am. Pharm. Ass., 1906, v. 54, p. 441. 
Eli Lilly & Co. are quoted as asserting that the U. S. P. VIII 
standard for fluid extract of pilocarpus is too low ; it should be 0.75 
gm. of alkaloid in 100 c, c. — Ibid., v. 54, p. 440. 
