461 
Nebraska, south to Florida and Arkansas. — Bull. Bur. Plant Ind., 
U. S. Dept. Agric., 1906, No. 89, p. 61. 
Francis, John M., thinks that the acetic fluid extracts form one of 
the few mistakes committed in this most splendid work [U. S. P. 
VIII].. See under Lobelia. — Bull. Pharm., Detroit, 1906, v. 20, 
p. 12. 
Fyfe, John William, says that Sanguinarict canadensis was exten- 
sively employed by the early eclectics. It was regarded by them as 
a remedy of great value in malignant scarlet fever and in pneumonia, 
and especially indicated when the expectoration was streaked Avith 
blood. — Eclectic M. J., Cincin., 1906, v. 66, p. 319. 
SANTONICA. 
Weigel, G., found santonica adulterated to the extent of 10 to 12 
per cent with the seeds of other plants. — Pharm. Zentralh., 1906, v. 
47, p. 891. 
SANTONINUM. 
Wedekind, E., presents a study of the history and composition of 
santonin with some observations on the basic properties of santonin, 
santoninsulphonic acid, and the constitution of santonin. — Arch. d. 
Pharm. Berl., 1906, v. 244, pp. 623-639. 
Riedel’s Berichte (Berk, 1906, p. 26) reports the melting point of 
a recrystallized santonin to be 169.5° C., on careful heating, and in an 
• air bath 172° C. 
Wiebelitz, H., suggests the adoption in the pharmacopoeia of the 
requirement found in Hager that 1 gm. of santonin should dissolve 
completely in 6 gm. of chloroform. — Pharm. Ztg. Berk, 1906, v. 51, 
p. 1004. 
Felter, Harvey Wickes, quotes several authors as to the value of 
santonin in diabetes mellitus, and adds that the drug opens up possi- 
bilities that seem to have been overlooked in its earlier history, and 
none will be more Avelcome than its good effects in diabetes if proven 
to be true. — Eclectic M. J., Cincin., 1906, v. 66, p. 343. 
Fyfe, J. W., (Eclectic Rev., October, 1905) discusses the use of 
santonin in the relief of the irritation, pain, and scalding sensations 
in the urethra Avhich are experienced by some women during and 
immediately after micturition. It is also a A^ery useful remedy where 
there is retention of urine in the advanced stages of acute diseases in 
children. — Abstr., Ibid ., p. 94. 
For additional references on the use of santonin, see Index Med- 
icus, J. Am. M. Ass. and Merck’s Ann. Rep., Darmstadt. 
SAPO. 
Fahrion, W., outlines a method for the analysis of soap in which 
he determines («) the total fat, ( b ) the total alkali, (c) the free 
