465 
Wiebelitz, H., believes that, in connection with vinegar of squill, it 
would be desirable to state that on keeping there is a gradual decrease 
in acidity. — Pharm. Ztg., Berl., 1906, v. 51, p. 1003. 
Caldwell, Paul, believes that acetic acid in sirups is objectionable, 
and suggests that an alcoholic extract of squill would make a more 
desirable sirup. — Drug. Circ. & Chem. Gaz., X. Y., 1906, v. 50, p. 159. 
He recommends the addition of 5 per cent of glycerin in the making 
of compound sirup of squill and filtering the mixture of fluid extracts 
and water through magnesium carbonate. — Ibid. 
Sear by, TY M., notes an apparent inconsistency between the doses 
of the sirup and the compound sirup of squill ; that of the former 
being equivalent to 1.35 grains of squill, of the latter to 2.4 grains, 
which carries with it 2.4 grains of senega and one-sixth grain of anti- 
mony and potassium tartrate — enough to nauseate, yet not enough to 
serve as an emetic. — Am. J. Pharm., Phila., 1906, v. 78, p. 209. 
Abraham, A. C., discusses the preparation of oxymel of squill, and 
points out some of the precautions to be observed. — Pharm. J., Lond., 
1906, v. 22, p. 213. 
A number of additional references to oxymel of squill Ph. Brit, 
will be found in Pharm. J., Bond., 1906, v. 22 and 23. 
Hajmes, G. S., says the most striking feature of the results obtained 
from his experiments is the superiority of squill over digitalis and 
stroplianthus as a cardiac stimulant. — Biochem. J., Liverpool, 1906, 
v. 1, pp. 62-87. 
Dixon, YT. E., comparing digitalis, squill, and stroplianthus, says 
that squill has the more powerful effect on ordinary cardiac muscle, 
and, provided the three drugs reach the circulation in equal amounts, 
it increases the output from the heart more than the other two. It 
has, however, the disadvantages that it is but slowly absorbed and 
tends to produce some constriction of the coronary vessels. — Brit. M. 
J., Lond:, 1906, v. 2, p. 1460. 
SCOPOLA. 
Moerk, Frank X., points out that the extract of scopola is required 
to be four times the strength of the drug. — Proc. Pennsylvania 
Pharm. Ass., 1906, p. 159. See Gordon’s comment under Belladonna 
Folia. 
SCOPOLAMINE HYDEOBROMIDUM. 
Gordin, H, M., reviews the progress made in the chemistry of 
scopolamine during the 3 ^ear 1905 and abstracts, at some length, the 
paper by E. Schmidt on scopoline. — Pharm. Bev., Milwaukee, 1906, 
v. 24, pp. 371-374. 
Beckurts, H., reports an examination made by Prochow to deter- 
mine the amount of scopolamine in Datura arborea. He found the 
11667— Bull. 5S— 09 30 
